Forward and reverse genetic approaches to synaptogenesis

被引：20

作者：

Broadie, K ^{[1
]}

机构：

[1] Univ Utah, Dept Biol, Salt Lake City, UT 84112 USA

来源：

CURRENT OPINION IN NEUROBIOLOGY | 1998年 / 8卷 / 01期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

D O I：

10.1016/S0959-4388(98)80016-0

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Genetic approaches at the neuromuscular synapse are leading investigation into the mechanisms of synaptogenesis. The marriage of classical (forward) and reverse genetic techniques allows the isolation and analysis of novel proteins involved in synaptic maturation and the functional in vivo characterization of previously identified synaptic proteins. Of particular interest are recent advances using mouse reverse genetics and Drosophila forward genetics.

引用

页码：128 / 138

页数：11

共 64 条

[41] CLONING AND CHARACTERIZATION OF HDLG - THE HUMAN HOMOLOG OF THE DROSOPHILA DISKS LARGE TUMOR-SUPPRESSOR BINDS TO PROTEIN-4.1
LUE, RA
MARFATIA, SM
BRANTON, D
CHISHTI, AH
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (21) : 9818 - 9822
[42] MARTIN H, 1994, J NEUROCHEM, V63, P2259
[43] MCMAHAN UJ, 1990, COLD SPRING HARB SYM, V55, P407
[44] SYNAPSE-ASSOCIATED EXPRESSION OF AN ACETYLCHOLINE RECEPTOR-INDUCING PROTEIN, ARIA/HEREGULIN, AND ITS PUTATIVE RECEPTORS, ERBB2 AND ERBB3, IN DEVELOPING MAMMALIAN MUSCLE
MOSCOSO, LM
CHU, GC
GAUTAM, M
NOAKES, PG
MERLIE, JP
SANES, JR
[J]. DEVELOPMENTAL BIOLOGY, 1995, 172 (01) : 158 - 169
[45] Naisbitt S, 1997, J NEUROSCI, V17, P5687
[46] PURIFICATION OF 14-3-3 PROTEIN AND ANALYSIS OF ISOFORMS IN CHICKEN BRAIN
PATEL, Y
MARTIN, H
HOWELL, S
JONES, D
ROBINSON, K
AITKEN, A
[J]. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 1994, 1222 (03): : 405 - 409
[47] Presynaptic development at the Drosophila neuromuscular junction: Assembly and localization of presynaptic active zones
Prokop, A
Landgraf, M
Rushton, E
Broadie, K
Bate, M
[J]. NEURON, 1996, 17 (04) : 617 - 626
[48] STIMULATION OF CATECHOLAMINE SECRETION FROM ADRENAL CHROMAFFIN CELLS BY 14-3-3-PROTEINS IS DUE TO REORGANIZATION OF THE CORTICAL ACTIN NETWORK
ROTH, D
BURGOYNE, RD
[J]. FEBS LETTERS, 1995, 374 (01) : 77 - 81
[49] Genetic analysis of postsynaptic differentiation at the vertebrate neuromuscular junction
Sanes, JR
[J]. CURRENT OPINION IN NEUROBIOLOGY, 1997, 7 (01) : 93 - 100
[50] Genetic dissection of structural and functional components of synaptic plasticity .2. Fasciclin II controls presynaptic structural plasticity
Schuster, CM
Davis, GW
Fetter, RD
Goodman, CS
[J]. NEURON, 1996, 17 (04) : 655 - 667

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