The diverse roles of Integrins and their ligands in angiogenesis

被引:94
作者
Hynes, RO [1 ]
Lively, JC
McCarty, JH
Taverna, D
Francis, SE
Hodivala-Dilke, K
Xiao, Q
机构
[1] MIT, Howard Hughes Med Inst, Cambridge, MA 02139 USA
[2] MIT, Ctr Canc Res, Cambridge, MA 02139 USA
关键词
D O I
10.1101/sqb.2002.67.143
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:143 / 153
页数:11
相关论文
共 96 条
[71]   Del1 induces integrin signaling and angiogenesis by ligation of αVβ3 [J].
Penta, K ;
Varner, JA ;
Liaw, L ;
Hidai, C ;
Schatzman, R ;
Quertermous, T .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (16) :11101-11109
[72]   Intrinsic activating properties of GP IIb/IIIa blockers [J].
Peter, K ;
Schwarz, M ;
Nordt, T ;
Bode, C .
THROMBOSIS RESEARCH, 2001, 103 :S21-S27
[73]   New functions for non-collagenous domains of human collagen type IV -: Novel integrin ligands inhibiting angiogenesis and tumor growth in vivo [J].
Petitclerc, E ;
Boutaud, A ;
Prestayko, A ;
Xu, JS ;
Sado, Y ;
Ninomiya, Y ;
Sarras, MP ;
Hudson, BG ;
Brooks, PC .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (11) :8051-8061
[74]   Suppression of angiogenesis by lentiviral delivery of PEX, a noncatalytic fragment of matrix metalloproteinase 2 [J].
Pfeifer, A ;
Kessler, T ;
Silletti, S ;
Cheresh, DA ;
Verma, IM .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (22) :12227-12232
[75]   Ligand binding to integrins [J].
Plow, EF ;
Haas, TK ;
Zhang, L ;
Loftus, J ;
Smith, JW .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (29) :21785-21788
[76]   Elevated matrix metalloprotease and angiostatin levels in integrin α1 knockout mice cause reduced tumor vascularization [J].
Pozzi, A ;
Moberg, PE ;
Miles, LA ;
Wagner, S ;
Soloway, P ;
Gardner, HA .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (05) :2202-2207
[77]   Low plasma levels of matrix metalloproteinase 9 permit increased tumor angiogenesis [J].
Pozzi, A ;
LeVine, WF ;
Gardner, HA .
ONCOGENE, 2002, 21 (02) :272-281
[78]   Interaction of endostatin with integrins implicated in angiogenesis [J].
Rehn, M ;
Veikkola, T ;
Kukk-Valdre, E ;
Nakamura, H ;
Ilmonen, M ;
Lombardo, CR ;
Pihlajaniemi, T ;
Alitalo, K ;
Vuori, K .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (03) :1024-1029
[79]   Enhanced pathological angiogenesis in mice lacking β3 integrin or β3 and β5 integrins [J].
Reynolds, LE ;
Wyder, L ;
Lively, JC ;
Taverna, D ;
Robinson, SD ;
Huang, XZ ;
Sheppard, D ;
Hynes, O ;
Hodivala-Dilke, KM .
NATURE MEDICINE, 2002, 8 (01) :27-34
[80]   Mechanisms of angiogenesis [J].
Risau, W .
NATURE, 1997, 386 (6626) :671-674