A concise synthesis of (2S,4R)- and (2S,4S)-4-methylglutamic acid

被引：9

作者：

Gu, ZQ

Li, M

机构：

[1] Sunmack Sci Inc, Gaithersburg, MD 20898 USA

[2] NIDDK, Med Chem Lab, NIH, Bethesda, MD 20892 USA

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 15期

关键词：

4-methylglutamic acid; synthesis; enantiomerically pure;

D O I：

10.1016/S0040-4039(03)00429-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A concise, multi-gram scale method for producing the bioactive and enantiomerically pure epimers, (2S,4R)- and (2S,4S)-glutamic acids, in a single synthetic scheme is described. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：3203 / 3205

页数：3

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