DNA methylation with a sting: an active DNA methylation system in the honeybee

被引：28

作者：

Schaefer, Matthias ^{[1
]}

Lyko, Frank ^{[1
]}

机构：

[1] Deutsch Krebsforschungszentrum, Div Epigenet, D-69120 Heidelberg, Germany

来源：

BIOESSAYS | 2007年 / 29卷 / 03期

关键词：

D O I：

10.1002/bies.20548

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The existence of DNA methylation in insects has been a controversial subject over a long period of time. The recently completed genome sequence of the honeybee Apis mellitera has revealed the first insect with a full complement of DNA methyltransferases.((1)) A parallel study demonstrated that these enzymes are catalytically active and that Apis genes can be methylated in specific patterns.((2)) These findings establish bees as a model to analyze the function of DNA methylation systems in invertebrate organisms and might also be important to understand evolutionary aspects of DNA methylation in higher eukaryotes.

引用

页码：208 / 211

页数：4

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