Prevention and control of biofilm-based medical-device-related infections

被引：363

作者：

Francolini, Iolanda ^{[3
]}

Donelli, Gianfranco ^{[1
,2
]}

机构：

[1] Ist Super Sanita, Dept Technol & Hlth, I-00161 Rome, Italy

[2] IRCCS Fdn Santa Lucia, Microbial Biofilm Lab, Rome, Italy

[3] Univ Roma La Sapienza, Dept Chem, I-00185 Rome, Italy

来源：

FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY | 2010年 / 59卷 / 03期

关键词：

medical device; polymers; biofilm; bacterial infection; fungal infection; antibiotics; CENTRAL VENOUS CATHETERS; IN-VITRO ACTIVITY; BLOOD-STREAM INFECTIONS; PSEUDOMONAS-AERUGINOSA; STAPHYLOCOCCUS-AUREUS; SILVER-SULFADIAZINE; CANDIDA-ALBICANS; URETHRAL CATHETER; PERSISTER CELLS; BONE CEMENTS;

D O I：

10.1111/j.1574-695X.2010.00665.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Biofilms play a pivotal role in healthcare-associated infections, especially those related to the implant of medical devices, such as intravascular catheters, urinary catheters and orthopaedic implants. This paper reviews the most successful approaches for the control and prevention of these infections as well as promising perspectives for the development of novel devices refractory to microbial adhesion, colonization and biofilm formation.

引用

页码：227 / 238

页数：12

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