A synthesis of a glycopeptide analogue of eel calcitonin

被引：33

作者：

Mizuno, M

Muramoto, I

Kawakami, T

Seike, M

Aimoto, S

Haneda, K

Inazu, T

机构：

[1] Noguchi Inst, Itabashi Ku, Tokyo 173, Japan

[2] Osaka Univ, Inst Prot Res, Suita, Osaka 565, Japan

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 1-2期

关键词：

D O I：

10.1016/S0040-4039(97)10487-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The glycopeptide analogue of eel calcitonin, [Asn(GlcNAc)(3)]-CT (1), in which N-acetylglucosamine (GlcNAc) is attached to the asparagine residue of the peptide was synthesized using a thioester method to build the polypeptide segment and a dimethylphosphinothioic mixed anhyride (Mpt-MA) method for the incorporation of the glycopeptide moiety. (C) 1997 Elsevier Science Ltd. All rights reserved.

引用

页码：55 / 58

页数：4

共 14 条

[1]

BLITHE DL, 1993, TRENDS GLYCOSCI GLYC, V5, P81

[2]

BRAMS IC, 1993, J CHEM SOC P1, P1461

[3]

Haneda K, 1996, CARBOHYD RES, V292, P61

[4] POLYPEPTIDE-SYNTHESIS USING THE S-ALKYL THIOESTER OF A PARTIALLY PROTECTED PEPTIDE SEGMENT - SYNTHESIS OF THE DNA-BINDING DOMAIN OF C-MYB PROTEIN (142-193)-NH2 [J].