A versatile approach to 3-alkyl and 2,3-dialkylpyrroles

被引：3

作者：

Burley, I

Bilic, B

Hewson, AT

Newton, JRA

机构：

[1] Sheffield Hallam Univ, Div Chem, Sheffield S1 1WB, S Yorkshire, England

[2] Sheffield Hallam Univ, Biomed Res Ctr, Sheffield S1 1WB, S Yorkshire, England

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 46期

基金：

英国工程与自然科学研究理事会;

关键词：

pyrrolines; aromatisation; pyrroles; intramolecular Wittig;

D O I：

10.1016/S0040-4039(00)01591-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A route is described towards N-benzoyl-3-alkyl and N-benzoyl-2,3-dialkyl pyrroles from alpha -amido-ketones via an intramolecular Wittig reaction to afford 4-phenylthio-3-pyrrolines which are then oxidised to the corresponding sulphones and aromatised by treatment with potassium t-butoxide. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：8969 / 8972

页数：4

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