An efficient synthesis of pyrroles by a one-pot, three-component condensation of a carbonyl compound, an amine and a nitroalkene in a molten ammonium salt

被引：84

作者：

Ranu, BC ^{[1
]}

Dey, SS ^{[1
]}

机构：

[1] Indian Assoc Cultivat Sci, Dept Organ Chem, Kolkata 700032, W Bengal, India

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 14期

关键词：

pyrrole; tetrabutylammonium bromide; condensation; solvent-free reaction;

D O I：

10.1016/S0040-4039(03)00439-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A one-pot, three-component condensation of a carbonyl compound, an amine and a nitroalkene leading to an efficient synthesis of alkyl-substituted pyrroles has been carried out in molten tetrabutyl ammonium bromide. Neither a catalyst nor an organic solvent is required for this reaction and the molten ammonium salt is recyclable. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：2865 / 2868

页数：4

共 28 条

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