Reward representations and reward-related learning in the human brain: insights from neuroimaging

被引:964
作者
O'Doherty, JP [1 ]
机构
[1] UCL, Neurol Inst, Wellcome Dept Imaging Neurosci, London WC1N 3BG, England
[2] CALTECH, Div Humanities & Social Sci, Pasadena, CA 91125 USA
关键词
D O I
10.1016/j.conb.2004.10.016
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
This review outlines recent findings from human neuroimaging concerning the role of a highly interconnected network of brain areas including orbital and medial prefrontal cortex, amygdala, striatum and dopaminergic mid-brain in reward processing. Distinct reward-related functions can be attributed to different components of this network. Orbitofrontal cortex is involved in coding stimulus reward value and in concert with the amygdala and ventral striatum is implicated in representing predicted future reward. Such representations can be used to guide action selection for reward, a process that depends, at least in part, on orbital and medial prefrontal cortex as well as dorsal striatum.
引用
收藏
页码:769 / 776
页数:8
相关论文
共 64 条
  • [31] Dissociable amygdala and orbitofrontal responses during reversal fear conditioning
    Morris, JS
    Dolan, RJ
    [J]. NEUROIMAGE, 2004, 22 (01) : 372 - 380
  • [32] A differential neural response in the human amygdala to fearful and happy facial expressions
    Morris, JS
    Frith, CD
    Perrett, DI
    Rowland, D
    Young, AW
    Calder, AJ
    Dolan, RJ
    [J]. NATURE, 1996, 383 (6603) : 812 - 815
  • [33] Beauty in a smile: the role of medial orbitofrontal cortex in facial attractiveness
    O'Doherty, J
    Winston, J
    Critchley, H
    Perrett, D
    Burt, DM
    Dolan, RJ
    [J]. NEUROPSYCHOLOGIA, 2003, 41 (02) : 147 - 155
  • [34] O'Doherty J, 2003, J NEUROSCI, V23, P7931
  • [35] Representation of pleasant and aversive taste in the human brain
    O'Doherty, J
    Rolls, ET
    Francis, S
    Bowtell, R
    McGlone, F
    [J]. JOURNAL OF NEUROPHYSIOLOGY, 2001, 85 (03) : 1315 - 1321
  • [36] Dissociable roles of ventral and dorsal striatum in instrumental conditioning
    O'Doherty, J
    Dayan, P
    Schultz, J
    Deichmann, R
    Friston, KJ
    Dolan, RJ
    [J]. SCIENCE, 2004, 304 (5669) : 452 - 454
  • [37] Sensory-specific satiety-related olfactory activation of the human orbitofrontal cortex
    O'Doherty, J
    Rolls, ET
    Francis, S
    Bowtell, R
    McGlone, F
    Kobal, G
    Renner, B
    Ahne, G
    [J]. NEUROREPORT, 2000, 11 (04) : 893 - 897
  • [38] Neural responses during anticipation of a primary taste reward
    O'Doherty, JP
    Deichmann, R
    Critchley, HD
    Dolan, RJ
    [J]. NEURON, 2002, 33 (05) : 815 - 826
  • [39] Temporal difference models and reward-related learning in the human brain
    O'Doherty, JP
    Dayan, P
    Friston, KJ
    Critchley, H
    Dolan, RJ
    [J]. NEURON, 2003, 38 (02) : 329 - 337
  • [40] Activity in human ventral striatum locked to errors of reward prediction
    Pagnoni, G
    Zink, CF
    Montague, PR
    Berns, GS
    [J]. NATURE NEUROSCIENCE, 2002, 5 (02) : 97 - 98