Early growth patterns and long-term obesity risk

被引:89
作者
Stettler, Nicolas [1 ]
Iotova, Violeta [2 ]
机构
[1] Univ Penn, Childrens Hosp Philadelphia, Sch Med, Div Gastroenterol Hepatol & Nutr, Philadelphia, PA 19104 USA
[2] Med Univ Varna, Clin Paediat Endocrinol, Varna, Bulgaria
关键词
adiposity; BMI; fetus; infancy; obesity; BODY-MASS INDEX; GESTATIONAL WEIGHT-GAIN; HIGH BIRTH-WEIGHT; POSTNATAL WEIGHT; EARLY-CHILDHOOD; BLOOD-PRESSURE; INFANT GROWTH; FAT MASS; AGE; OVERWEIGHT;
D O I
10.1097/MCO.0b013e328337d7b9
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose of review This review is an update on recent findings regarding early growth patterns and later obesity. These data are important because the potential programming of obesity in early life provides hope for new prevention strategies targeting early growth for long-term benefits. Recent findings Recent findings regarding the association of childhood or adulthood obesity with fetal growth, gestational weight gain, maternal diabetes, or infancy weight gain are reviewed. Some related outcomes and potential mechanisms are also described. Most studies remain observational and confirm previous findings, but some intervention studies have begun to appear in the recent literature and support some, but not other, observed associations. Summary Past and recent findings confirm the association of early growth patterns with obesity. However, causality must be demonstrated and safety must be established before translating these findings into public health recommendations.
引用
收藏
页码:294 / 299
页数:6
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