Early growth patterns and long-term obesity risk

被引:89
作者
Stettler, Nicolas [1 ]
Iotova, Violeta [2 ]
机构
[1] Univ Penn, Childrens Hosp Philadelphia, Sch Med, Div Gastroenterol Hepatol & Nutr, Philadelphia, PA 19104 USA
[2] Med Univ Varna, Clin Paediat Endocrinol, Varna, Bulgaria
关键词
adiposity; BMI; fetus; infancy; obesity; BODY-MASS INDEX; GESTATIONAL WEIGHT-GAIN; HIGH BIRTH-WEIGHT; POSTNATAL WEIGHT; EARLY-CHILDHOOD; BLOOD-PRESSURE; INFANT GROWTH; FAT MASS; AGE; OVERWEIGHT;
D O I
10.1097/MCO.0b013e328337d7b9
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose of review This review is an update on recent findings regarding early growth patterns and later obesity. These data are important because the potential programming of obesity in early life provides hope for new prevention strategies targeting early growth for long-term benefits. Recent findings Recent findings regarding the association of childhood or adulthood obesity with fetal growth, gestational weight gain, maternal diabetes, or infancy weight gain are reviewed. Some related outcomes and potential mechanisms are also described. Most studies remain observational and confirm previous findings, but some intervention studies have begun to appear in the recent literature and support some, but not other, observed associations. Summary Past and recent findings confirm the association of early growth patterns with obesity. However, causality must be demonstrated and safety must be established before translating these findings into public health recommendations.
引用
收藏
页码:294 / 299
页数:6
相关论文
共 46 条
[31]   Infant feeding and obesity at 11 years: Prospective birth cohort study [J].
Neutzling, Marilda Borges ;
Curi Hallal, Pedro Rodrigues ;
Pavin Araujo, Cora Luiza ;
Horta, Bernardo Lessa ;
Alves Vieira, Maria De Fatima ;
Baptista Menezes, Ana Maria ;
Victora, Cesar Gomes .
INTERNATIONAL JOURNAL OF PEDIATRIC OBESITY, 2009, 4 (03) :143-149
[32]   Infancy Weight Gain Predicts Childhood Body Fat and Age at Menarche in Girls [J].
Ong, Ken K. ;
Emmett, Pauline ;
Northstone, Kate ;
Golding, Jean ;
Rogers, Imogen ;
Ness, Andrew R. ;
Wells, Jonathan C. ;
Dunger, David B. .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2009, 94 (05) :1527-1532
[33]   Common polymorphic variation in the genetically diverse African insulin gene and its association with size at birth [J].
Petry, Clive J. ;
Rayco-Solon, Pura ;
Fulford, Anthony J. C. ;
Stead, John D. H. ;
Wingate, Dianne L. ;
Ong, Ken K. ;
Sirugo, Giorgio ;
Prentice, Andrew M. ;
Dunger, David B. .
HUMAN GENETICS, 2009, 126 (03) :375-384
[34]   Success of Programming Fetal Growth Phenotypes Among Obese Women [J].
Salihu, Hamisu M. ;
Mbah, Alfred K. ;
Alio, Amina P. ;
Kornosky, Jennifer L. ;
Bruder, Karen ;
Belogolovkin, Victoria .
OBSTETRICS AND GYNECOLOGY, 2009, 114 (02) :333-339
[35]   Gestational weight gain in relation to offspring body mass index and obesity from infancy through adulthood [J].
Schack-Nielsen, L. ;
Michaelsen, K. F. ;
Gamborg, M. ;
Mortensen, E. L. ;
Sorensen, T. I. A. .
INTERNATIONAL JOURNAL OF OBESITY, 2010, 34 (01) :67-74
[36]  
Shehadeh N, 2008, J PEDIATR ENDOCR MET, V21, P9
[37]   BMI peak in infancy as a predictor for later BMI in the Uppsala Family Study [J].
Silverwood, R. J. ;
De Stavola, B. L. ;
Cole, T. J. ;
Leon, D. A. .
INTERNATIONAL JOURNAL OF OBESITY, 2009, 33 (08) :929-937
[38]   An obesogenic postnatal environment is more important than the fetal environment for the development of adult adiposity: a study of female twins [J].
Skidmore, Paula M. L. ;
Cassidy, Aedin ;
Swaminathan, Ramasamyiyer ;
Richards, J. Brent ;
Mangino, Massimo ;
Spector, Tim D. ;
MacGregor, Alex J. .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2009, 90 (02) :401-406
[39]   Placental determinants of fetal growth: Identification of key factors in the insulin-like growth factor and cytokine systems using artificial neural networks [J].
Street M.E. ;
Grossi E. ;
Volta C. ;
Faleschini E. ;
Bernasconi S. .
BMC Pediatrics, 8 (1)
[40]   Weight Status in the First 6 Months of Life and Obesity at 3 Years of Age [J].
Taveras, Elsie M. ;
Rifas-Shiman, Sheryl L. ;
Belfort, Mandy B. ;
Kleinman, Ken P. ;
Oken, Emily ;
Gillman, Matthew W. .
PEDIATRICS, 2009, 123 (04) :1177-1183