A model for post-occlusive reactive hyperemia as measured with laser-Doppler perfusion monitoring

被引:26
作者
de Mul, FFM
Morales, F
Smit, AJ
Graaff, R
机构
[1] Univ Groningen, Dept Biomed Engn, Fac Med, NL-9713 AV Groningen, Netherlands
[2] Univ Groningen, Dept Med, Fac Med, NL-9713 AV Groningen, Netherlands
关键词
diabetes mellitus; laser doppler perfusion monitoring; PAOD; peripheral arterial occlusive disease; PORH; post-occlusive reactive hyperaemia;
D O I
10.1109/TBME.2004.840507
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
To facilitate the quantitative analysis of post-occlusive reactive fiyper emia (POR11), measured with laser-Doppler perfusion monitoring (LDPM) on extremities, we present a flow model for the dynamics of the perfusion of the tissue during PORH, based on three parameters: two time constants (tau(1) and tau(2)) and the ratio of the maximum flux and, the resting flux. With these three constants quantitative comparisons between experiments will be possible and, therefore, we propose to adopt this approach as future standard. For this reason, we also developed a computer program to perform the fit of the model to measured data.
引用
收藏
页码:184 / 190
页数:7
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