Substituted quinolines induce inhibition of proliferation of HTLV-1 infected cells

被引:74
作者
Fournet, A
Mahieux, R
Fakhfakh, MA
Franck, X
Hocquemiller, R
Figadère, B
机构
[1] Univ Paris Sud, Fac Pharm, CNRS, BioCIS,Lab Pharmacognosie, F-92296 Chatenay Malabry, France
[2] Inst Rech Dev, F-75480 Paris, France
[3] Inst Pasteur, Unite Epidemiol & Physiopathol Virus Oncogenes, F-75724 Paris, France
关键词
D O I
10.1016/S0960-894X(02)01085-5
中图分类号
R914 [药物化学];
学科分类号
100701 [药物化学];
摘要
Several quinolines were synthesized and evaluated against HTLV-1 infected cells. Some of them were able to inhibit HTLV-1 cell-growth at 10 muM. Some structure-activity relationships were observed. (C) 2003 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:891 / 894
页数:4
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