Catalytic oxidation of isosafrol by vanadium complexes

被引：16

作者：

Alvarez, Heiddy Marquez

De Andrade, Joyce L.

Pereira, Nei, Jr.

Muri, Estela M. F.

Horn, Adolfo, Jr.

Barbosa, Dayse Pereira

Antunes, O. A. C.

机构：

[1] Univ Fed Rio de Janeiro, Inst Quim, BR-21945970 Rio de Janeiro, Brazil

[2] Univ Fed Rio de Janeiro, Escola Quim, BR-21945970 Rio de Janeiro, Brazil

[3] Univ Fed Fluminense, Fac Farm, BR-24241000 Niteroi, RJ, Brazil

[4] UENF, Lab Ciencias Quim, BR-28013602 Rio Janerio, Brazil

[5] Univ Fed Rio de Janeiro, Ilha Fundao, Nucleo Pesquisas Prod Nat, BR-21941590 Rio de Janeiro, Brazil

来源：

CATALYSIS COMMUNICATIONS | 2007年 / 8卷 / 09期

关键词：

oxidation; catalysis; hydrogen peroxide; t-butyl hydroperoxide; aldehyde production; epoxidation;

D O I：

10.1016/j.catcom.2006.11.021

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

1,2-methylenedioxy-4(1-propenyl)benzene, isosafrol (1a), is an important intermediate for the synthesis of drugs like L-DOPA. In this work, different vanadium complexes have been evaluated as catalysts for the preparation of the corresponding double bond cleavage product, 3,4-methylenedioxybenzaldehyde, piperonal (2), and the corresponding epoxide, 2-methyl-3-[3',4'-methylenedioxyphenyl]oxirane (3). When VCl2(salen) is used either with H2O2 60% or TBHP (5 M isooctane solution), the epoxide was the major product obtained in very good yields. (c) 2006 Elsevier B.V. All rights reserved.

引用

页码：1336 / 1340

页数：5

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