Fungal meningitis

被引:96
作者
Gottfredsson, M
Perfect, JR [1 ]
机构
[1] Duke Univ, Med Ctr, Dept Med, Div Infect Dis & Int Hlth, Durham, NC 27710 USA
[2] Natl Univ Hosp Reykjavik, Landspitalinn, Dept Med, Infect Dis Sect, Reykjavik, Iceland
关键词
meningitis; fungi; central nervous system infections;
D O I
10.1055/s-2000-9394
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Fungi provide many benefits to humans. However, some of these fungi have the ability to become human pathogens. All the major fungal pathogens can produce meningitis. From the common cryptococcal meningitis to the rare fungal meningitis caused by a dimorphic or filamentous fungus, medical issues are discussed in this review on a fungus-specific basis. Both primary (Cryptococcus, Blastomyces, Histoplasma, Coccidioides, and other dimorphic fungi) and secondary (Aspergillus, Candida, and a series of molds) fungal pathogens can produce life-threatening central nervous system infections. These infections require immediate and precise diagnosis and carefully selected management strategies to optimize outcomes. In this review, we examine the epidemiology, pathogenesis, clinical manifestations, and treatment for fungal meningitis in all the major fungal groups.
引用
收藏
页码:307 / 322
页数:16
相关论文
共 208 条
  • [91] MENINGITIS DUE TO SPOROTRICHUM SCHENCKII
    KLEIN, RC
    IVENS, MS
    SEABURY, JH
    DASCOMB, HE
    [J]. ARCHIVES OF INTERNAL MEDICINE, 1966, 118 (02) : 145 - &
  • [92] CRYPTOCOCCOSIS IN THE ACQUIRED IMMUNODEFICIENCY SYNDROME
    KOVACS, JA
    KOVACS, AA
    POLIS, M
    WRIGHT, WC
    GILL, VJ
    TUAZON, CU
    GELMANN, EP
    LANE, HC
    LONGFIELD, R
    OVERTURF, G
    MACHER, AM
    FAUCI, AS
    PARRILLO, JE
    BENNETT, JE
    MASUR, H
    [J]. ANNALS OF INTERNAL MEDICINE, 1985, 103 (04) : 533 - 538
  • [93] CHRONIC BLASTOMYCOTIC MENINGITIS
    KRAVITZ, GR
    DAVIES, SF
    ECKMAN, MR
    SAROSI, GA
    [J]. AMERICAN JOURNAL OF MEDICINE, 1981, 71 (03) : 501 - 505
  • [94] Invasive infections due to Clavispora lusitaniae
    Krcmery, V
    Mateicka, F
    Grausova, S
    Kunova, A
    Hanzen, J
    [J]. FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY, 1999, 23 (01): : 75 - 78
  • [95] KRCMERY V, 1994, CHEMOTHERAPY, V40, P70
  • [96] ENCAPSULATION AND MELANIN FORMATION AS INDICATORS OF VIRULENCE IN CRYPTOCOCCUS-NEOFORMANS
    KWONCHUNG, KJ
    RHODES, JC
    [J]. INFECTION AND IMMUNITY, 1986, 51 (01) : 218 - 223
  • [97] ASPERGILLOSIS OF THE SPHENOID SINUS SIMULATING A PITUITARY-TUMOR
    LARRANAGA, J
    FANDINO, J
    GOMEZBUENO, J
    RODRIGUEZ, D
    GONZALEZCARRERO, J
    BOTANA, C
    [J]. NEURORADIOLOGY, 1989, 31 (04) : 362 - 363
  • [98] FLUCONAZOLE COMPARED WITH AMPHOTERICIN-B PLUS FLUCYTOSINE FOR CRYPTOCOCCAL MENINGITIS IN AIDS - A RANDOMIZED TRIAL
    LARSEN, RA
    LEAL, MAE
    CHAN, LS
    [J]. ANNALS OF INTERNAL MEDICINE, 1990, 113 (03) : 183 - 187
  • [99] Comparative study of mortality and morbidity in premature infants (birth weight, <1,250 g) with candidemia or candidal meningitis
    Lee, BE
    Cheung, PY
    Robinson, JL
    Evanochko, C
    Robertson, CMT
    [J]. CLINICAL INFECTIOUS DISEASES, 1998, 27 (03) : 559 - 565
  • [100] Liposomal amphotericin B (AmBisome) compared with amphotericin B both followed by oral fluconazole in the treatment of AIDS-associated cryptococcal meningitis
    Leenders, ACAP
    Reiss, P
    Portegies, P
    CLezy, K
    Hop, WCJ
    Hoy, J
    Borleffs, JCC
    Allworth, T
    Kauffmann, RH
    Jones, P
    Kroon, FP
    Verbrugh, HA
    deMarie, S
    [J]. AIDS, 1997, 11 (12) : 1463 - 1471