Genetics of anxiety disorders

被引：36

作者：

Arnold P.D. ^{[1
]}

Zai G. ^{[1
]}

Richter M.A. ^{[1
]}

机构：

[1] Anxiety Disorders Clinic, Centre for Addiction/Mental Health, University of Toronto, Toronto, Ont. M5T 1R8

来源：

Current Psychiatry Reports | 2004年 / 6卷 / 4期

基金：

英国医学研究理事会;

关键词：

Anxiety Disorder; Panic Disorder; Panic Disorder; Harm Avoidance; Myelin Oligodendrocyte Glycoprotein;

D O I：

10.1007/s11920-004-0073-1

中图分类号：

学科分类号：

摘要：

There is considerable evidence that genetic determinants play a major role in the etiology of anxiety. Investigations into susceptibility genes for anxiety are well underway, particularly for panic disorder and obsessive-compulsive disorder and more broadly defined anxiety-related traits, such as neuroticism and harm avoidance. This review will discuss some of the core issues related to diagnosis and molecular genetic methodology, followed by a review of recent molecular genetic findings for anxiety. The authors will attempt to highlight the numerous convergent and exciting findings. Given the rapid acceleration in knowledge of the human genome, a more definitive understanding of the genetic roots of these complex conditions may be anticipated in the relatively near future. Copyright © 2004 by Current Science Inc.

引用

页码：243 / 254

页数：11

共 115 条

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