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THE LEUKEMIA INHIBITORY FACTOR-RECEPTOR (LIFR) GENE IS LOCATED WITHIN A CLUSTER OF CYTOKINE RECEPTOR LOCI ON MOUSE CHROMOSOME-15 AND HUMAN CHROMOSOME-5P12-P13

被引：33
作者：
GEARING, DP
DRUCK, T
HUEBNER, K
OVERHAUSER, J
GILBERT, DJ
COPELAND, NG
JENKINS, NA
机构：
[1] THOMAS JEFFERSON UNIV,JEFFERSON MED COLL,JEFFERSON CANC INST,PHILADELPHIA,PA 19107
[2] THOMAS JEFFERSON UNIV,JEFFERSON INST MOLEC MED,DEPT BIOCHEM & MOLEC BIOL,PHILADELPHIA,PA 19107
[3] NCI,FREDERICK CANC RES & DEV CTR,ABL BASIC RES PROGRAM,FREDERICK,MD 21702
来源：
GENOMICS | 1993年 / 18卷 / 01期
关键词：
D O I：
10.1006/geno.1993.1441
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The leukemia inhibitory factor receptor (LIFR) gene was localized to human chromosome 5p12-p13 by somatic cell hybrid analysis. Interspecific backcross analysis revealed that the murine locus was on chromosome 15 in a region of homology with human chromosome 5p. In both human and mouse genomes, the LlFR locus was linked to the genes encoding the receptors for interleukin-7, prolactin, and growth hormone. © 1993 Academic Press, Inc.
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页码：148 / 150
页数：3
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