SYNTHESIS OF OPTICALLY-ACTIVE 5'-NORARISTEROMYCIN - ENZYME-CATALYZED KINETIC RESOLUTION OF 9-(4-HYDROXYCYCLOPENT-2-ENYL)PURINES

被引:28
作者
MERLO, V [1 ]
REECE, FJ [1 ]
ROBERTS, SM [1 ]
GREGSON, M [1 ]
STORER, R [1 ]
机构
[1] GLAXO GRP RES LTD,DEPT MED CHEM,GREENFORD UB6 0HE,MIDDX,ENGLAND
来源
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1993年 / 15期
关键词
D O I
10.1039/p19930001717
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A facile chemo-enzymatic route to optically active 5'-noraristeromycin from the epoxide 2 employs an enantioselective Pseudomonas cepacia lipase-catalysed acetylation
引用
收藏
页码:1717 / 1718
页数:2
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