A RADICAL CYCLIZATION APPROACH TO 1-ALPHA,25-DIHYDROXYVITAMIN-D3

被引：12

作者：

BATTY, D

CRICH, D

机构：

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1991年 / 11期

关键词：

D O I：

10.1039/p19910002894

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An approach to 1-alpha,25-dihydroxyvitamin D3 involving the preparation of the vinyl selenide 8, its cyclization to 9 with tributyltin hydride and the conversion of the latter into the known isomeric dienes 3 and 10 is described.

引用

页码：2894 / 2895

页数：2

共 10 条

[1] STEREOCONTROLLED TOTAL SYNTHESIS OF "1-ALPHA,25-DIHYDROXYCHOLECALCIFEROL AND 1-ALPHA,25-DIHYDROXYERGOCALCIFEROL
BAGGIOLINI, EG
IACOBELLI, JA
HENNESSY, BM
BATCHO, AD
SERENO, JF
USKOKOVIC, MR
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1986, 51 (16) : 3098 - 3108
[2] ACYL RADICAL CYCLIZATIONS IN SYNTHESIS .3. SYNTHESIS OF (+/-)-TRANS-3,5-BIS-(TERT-BUTYLDIMETHYLSILOXY)-2-METHYLENECYCLOHEXANONE, AN A-RING MODEL FOR 1-ALPHA, 25-DIHYDROXYVITAMIN-D3
BATTY, D
CRICH, D
FORTT, SM
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1990, (11): : 2875 - 2879
[3] SYNTHESIS OF A 1-ALPHA,25-DIHYDROXYVITAMIN-D3 A-RING MODEL BY AN ACYL RADICAL CYCLIZATION
BATTY, D
CRICH, D
FORTT, SM
[J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1989, (18) : 1366 - 1368
[4] C-ACYLATION UNDER VIRTUALLY NEUTRAL CONDITIONS
BROOKS, DW
LU, LDL
MASAMUNE, S
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1979, 18 (01): : 72 - 74
[5] JONES G, 1987, STEROIDS, V49, P1
[6] PHASE-TRANSFER CATALYSIS - PHOSPHORYLATION OF BETA-DICARBONYL COMPOUNDS
JONES, RA
BADESHA, SS
[J]. SYNTHETIC COMMUNICATIONS, 1981, 11 (07) : 557 - 560
[7] CONTROL OF STEREOSELECTIVITY IN SAMARIUM METAL INDUCED CYCLOPROPANATIONS - SYNTHESIS OF 1,25-DIHYDROXYCHOLECALCIFEROL
KABAT, M
KIEGIEL, J
COHEN, N
TOTH, K
WOVKULICH, PM
USKOKOVIC, MR
[J]. TETRAHEDRON LETTERS, 1991, 32 (21) : 2343 - 2346
[8] ULTRASONIC FORMATION AND REACTIONS OF SODIUM PHENYLSELENIDE
LEY, SV
ONEIL, IA
LOW, CMR
[J]. TETRAHEDRON, 1986, 42 (19) : 5363 - 5368
[9] ASYMMETRIC TOTAL SYNTHESIS OF AN A-RING PRECURSOR TO HORMONALLY ACTIVE 1-ALPHA,25-DIHYDROXYVITAMIN-D3
POSNER, GH
KINTER, CM
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1990, 55 (13) : 3967 - 3969
[10] A NEW SYNTHETIC ROUTE TO 1,25-DIHYDROXY-VITAMIN D-3
WILSON, SR
VENKATESAN, AM
AUGELLISZAFRAN, CE
YASMIN, A
[J]. TETRAHEDRON LETTERS, 1991, 32 (21) : 2339 - 2342

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