SYNTHESIS OF 2',3'-DIDEOXY-2',3'-DIDEHYDRONUCLEOSIDE ANALOGS AS POTENTIAL ANTI-HIV AGENTS

被引：6

作者：

DENAPOLI, L ^{[1
]}

MESSERE, A ^{[1
]}

MONTESARCHIO, D ^{[1
]}

PICCIALLI, G ^{[1
]}

SANTACROCE, C ^{[1
]}

机构：

[1] NAPLES UNIV,DIPARTIMENTO CHIM ORGAN & BIOL,VIA MEZZOCANNONE 16,I-80134 NAPLES,ITALY

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1992年 / 2卷 / 04期

关键词：

D O I：

10.1016/S0960-894X(01)80208-0

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The 4-substituted pyrimidine 2',3'-dideoxy-2',3'-didehydronucleosides 3 - 10 have been synthesized and the activity of compounds 8 - 10 against HIV evaluated. The synthesis of the 5'-phosphate derivatives 13 - 14 was also reported.

引用

页码：315 / 318

页数：4

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