REACTIVITY OF ANTIERYTHROCYTE ANTIBODY-INDUCED BY BABESIA-GIBSONI INFECTION AGAINST AGED ERYTHROCYTES

被引：17

作者：

MORITA, T

SAEKI, H

IMAI, S

ISHII, T

机构：

[1] Department of Parasitology, Nippon Veterinary and Animal Science University, Musashino-shi, Tokyo, 180

来源：

VETERINARY PARASITOLOGY | 1995年 / 58卷 / 04期

关键词：

BABESIA GIBSONI; DOG; ANEMIA; PATHOLOGY-PROTOZOA;

D O I：

10.1016/0304-4017(94)00726-S

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Effects of ageing treatment of erythrocytes to binding activity of the anti-erythrocyte antibody(s) in the serum of dogs infected artificially with Babesia gibsoni were examined by enzyme-linked immunosorbent assay (ELISA) using fixed cell antigen. When erythrocytes made senescent by two artificial ageing treatments, one of which was storing erythrocytes at 37 degrees C in medium for some days and the other was oxidation of erythrocytes with phenylhydrazine, reactivity of anti-erythrocyte antibody(s) in the infected serum to both types of treated erythrocytes was increased. These results suggest that such antibody(s) could play a role as one of the causes of anemia in canine babesiosis.

引用

页码：291 / 299

页数：9

共 24 条

[1] ANTIERYTHROCYTE MEMBRANE ANTIBODIES DETECTED IN SERA OF DOGS NATURALLY INFECTED WITH BABESIA-GIBSONI [J].