SYNTHETIC RECEPTORS BASED ON VINYLOGOUS SULFONYL PEPTIDES

被引：85

作者：

GENNARI, C

NESTLER, HP

SALOM, B

STILL, WC

机构：

[1] COLD SPRING HARBOR LAB,COLD SPRING HARBOR,NY 11724

[2] UNIV MILAN,DIPARTIMENTO CHIM ORGAN & IND,MILAN,ITALY

[3] COLUMBIA UNIV,DEPT CHEM,NEW YORK,NY 10027

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1995年 / 34卷 / 16期

关键词：

COMBINATORIAL CHEMISTRY; PEPTIDE ANALOGS; RECEPTORS; SUPRAMOLECULAR CHEMISTRY;

D O I：

10.1002/anie.199517651

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The tripeptide sequence (L‐Pro)‐(D‐Val)‐(D‐Pro) is recognized by a tweezerlike molecular receptor constructed from vinylogous sulfonyl peptides (see diagram on the right). The screening of this tweezer molecule against a combinatorial tripeptide library reveals interesting sequence specifities for this new class of receptors. DR = dye molecule (Disperse Red 1), • = polystyrene support. (Figure Presented.) Copyright © 1995 by VCH Verlagsgesellschaft mbH, Germany

引用

页码：1765 / 1768

页数：4

共 28 条

[1] SYNTHETIC RECEPTOR-BINDING ELUCIDATED WITH AN ENCODED COMBINATORIAL LIBRARY
BORCHARDT, A
STILL, WC
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (01) : 373 - 374
[2] SYNTHETIC RECEPTOR FOR INTERNAL RESIDUES OF A PEPTIDE-CHAIN - HIGHLY SELECTIVE BINDING OF (L)X-(L)PRO-(L),X TRIPEPTIDES
BORCHARDT, A
STILL, WC
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (16) : 7467 - 7468
[3] PEPTIDOSTEROIDAL RECEPTORS FOR OPIOID-PEPTIDES - SEQUENCE-SELECTIVE BINDING USING A SYNTHETIC RECEPTOR LIBRARY
BOYCE, R
LI, G
NESTLER, HP
SUENAGA, T
STILL, WC
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (17) : 7955 - 7956
[4] SOLID-PHASE SYNTHESIS OF PHOSPHONOPEPTIDES
CAMPAGNE, JM
COSTE, J
JOUIN, P
[J]. TETRAHEDRON LETTERS, 1995, 36 (12) : 2079 - 2082
[5] SOLID-PHASE SYNTHESIS OF PEPTIDYLPHOSPHONATES
CAMPBELL, DA
BERMAK, JC
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (13) : 6039 - 6040
[6] APPLICATIONS OF COMBINATORIAL TECHNOLOGIES TO DRUG DISCOVERY .1. BACKGROUND AND PEPTIDE COMBINATORIAL LIBRARIES
GALLOP, MA
BARRETT, RW
DOWER, WJ
FODOR, SPA
GORDON, EM
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1994, 37 (09) : 1233 - 1251
[7] GALLOP MA, 1994, J MED CHEM, V37, P1385
[8] SOLID-PHASE SYNTHESIS OF VINYLOGOUS SULFONYL PEPTIDES
GENNARI, C
NESTLER, HP
SALOM, B
STILL, WC
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1995, 34 (16): : 1763 - 1765
[9] GENNARI C, 1994, ANGEW CHEM INT EDIT, V33, P2067, DOI 10.1002/anie.199420671
[10] GENNARI C, 1995, ANGEW CHEM INT EDIT, V107, P1892

← 1 2 3 →