The LysM receptor kinase CERK1 mediates bacterial perception in Arabidopsis

被引:80
作者
Gimenez-Ibanez, Selena [1 ]
Ntoukakis, Vardis [1 ]
Rathjen, John P. [1 ]
机构
[1] Sainsbury Lab, Norwich NR4 7UH, Norfolk, England
关键词
PAMP; PRR; PTI; LysM; chitin; bacteria; carbohydrate;
D O I
10.4161/psb.4.6.8697
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Plants use pattern recognition receptors (PRRs) to perceive pathogen-associated molecular pattern (PAMPs) and initiate defence responses. PAMP-triggered immunity (PTI) plays an important role in general resistance, and constrains the growth of most microbes on plants. Despite the importance of PRRs in plant immunity, the vast majority of them remain to be identified. We recently showed that the Arabidopsis LysM receptor kinase CERK1 is required not only for chitin signalling and fungal resistance, but plays an essential role in restricting bacterial growth on plants. We proposed that CERK1 may mediate the perception of a bacterial PAMP, or an endogenous plant cell wall component released during infection, through its extracellular carbohydrate-binding LysM-motifs. Here we report reduced activation of a PAMP-induced defence response on plants lacking the CERK1 gene after treatment with crude bacterial extracts. This demonstrates that CERK1 mediates perception of an unknown bacterial PAMP in Arabidopsis.
引用
收藏
页码:539 / 541
页数:3
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