COMPARATIVE PHYSIOLOGICALLY BASED PHARMACOKINETICS OF HEXOBARBITAL, PHENOBARBITAL, AND THIOPENTAL IN THE RAT

被引：87

作者：

IGARI, Y ^{[1
]}

SUGIYAMA, Y ^{[1
]}

AWAZU, S ^{[1
]}

HANANO, M ^{[1
]}

机构：

[1] TOKYO COLL PHARM,DIV BIOPHARM,HACHIOJI,TOKYO 19203,JAPAN

来源：

JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS | 1982年 / 10卷 / 01期

关键词：

D O I：

10.1007/BF01059183

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：53 / 75

页数：23

共 35 条

[11]

FILOUS N, 1976, N-S ARCH PHARMACOL, V293, pR46

[12]

GOLDBAUM LR, 1954, J PHARMACOL EXP THER, V111, P197

[13]

GOODMAN LS, 1975, PHARM BASIS THERAPEU, P105

[14] INCREASED SYNTHESIS AND INHIBITED BREAKDOWN DURING INCREASE OF MICROSOMAL CYTOCHROMES P-450 AND B-5 AFTER PHENOBARBITAL [J].

GREIM, H .

NAUNYN-SCHMIEDEBERGS ARCHIV FUR PHARMAKOLOGIE, 1970, 266 (03) :261-&

[15]

HANANO M, 1978, D2TCRKM U TOK COMP C

[16] REVIEW OF THE APPLICATIONS OF PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELING [J].

HIMMELSTEIN, KJ ;

LUTZ, RJ .

JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS, 1979, 7 (02) :127-145

[17]

JOLLY JG, 1975, DRUG METAB DISP, V3, P577

[18] CORRELATION BETWEEN INVITRO AND INVIVO DRUG-METABOLISM RATE - OXIDATION OF ETHOXYBENZAMIDE IN RAT [J].

LIN, JH ;

HAYASHI, M ;

AWAZU, S ;

HANANO, M .

JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS, 1978, 6 (04) :327-337

[19] KINETIC-STUDIES ON THE DEETHYLATION OF ETHOXYBENZAMIDE - A COMPARATIVE-STUDY WITH ISOLATED HEPATOCYTES AND LIVER-MICROSOMES OF RAT [J].

LIN, JH ;

SUGIYAMA, Y ;

AWAZU, S ;

HANANO, M .

BIOCHEMICAL PHARMACOLOGY, 1980, 29 (20) :2825-2830

[20]

LIN YJ, 1973, CHEM PHARM BULL, V21, P2749

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