AN EASY ACCESS TO OPTICALLY PURE (R)-MALIC ACID VIA ENANTIOSELECTIVE HYDROLYSIS OF DIETHYL MALATE BY RHIZOPUS LIPASE

被引：5

作者：

USHIO, K

NAKAGAWA, K

WATANABE, K

机构：

[1] Department of Industrial Chemistry, Niihama National College of Technology, Niihama, Ehime, 792, Yakumo

来源：

BIOTECHNOLOGY LETTERS | 1992年 / 14卷 / 09期

关键词：

D O I：

10.1007/BF01029141

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Racemic diethyl malate was enantioselectively hydrolyzed by crude Rhizopus lipase (Saiken) to leave optically pure (greater-than-or-equal-to 99% ee) (R)-(+)- malate in c.a. 20% recovery. The combination of dipropyl malate and lipase AY (Amano) also gave (R)-enantiomer with a high ee of greater-than-or-equal-to 97% and about 20% recovery in a short reaction time.

引用

页码：795 / 800

页数：6

共 23 条

[21] STUDIES ON THE SYNTHESES OF THE APLYSIATOXINS - SYNTHESIS OF A SELECTIVELY-PROTECTED FORM OF THE C-27-C-30 (DIHYDROXYBUTANOATE) MOIETY OF OSCILLATOXIN-A [J].