ASSAYS TO MEASURE NANOMOLAR LEVELS OF THE RENIN INHIBITOR CGP 38 560 IN PLASMA

被引：12

作者：

CUMIN, F ^{[1
]}

DEGASPARO, M ^{[1
]}

WOOD, JM ^{[1
]}

SCHNELL, C ^{[1
]}

FRUEH, F ^{[1
]}

GRAF, P ^{[1
]}

机构：

[1] CIBA GEIGY AG, DEPT RES & DEV, DIV PHARMACEUT, CH-4002 BASEL, SWITZERLAND

来源：

HYPERTENSION | 1989年 / 14卷 / 04期

关键词：

D O I：

10.1161/01.HYP.14.4.379

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

引用

页码：379 / 384

页数：6

共 14 条

[1]

BOGER J, 1985, REGUL PEPTIDES, P8

[2] TRITIATED PEPTIDES .14. CATALYTIC EXCHANGE LABELING OF VARIOUS SYNTHETIC PEPTIDES [J].

BRUNDISH, DE ;

COMBE, MG ;

WADE, R .

JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 1983, 20 (07) :869-886

[3] A POTENT RADIOLABELED HUMAN RENIN INHIBITOR, [H-3] SR42128 - ENZYMATIC, KINETIC, AND BINDING-STUDIES TO RENIN AND OTHER ASPARTIC PROTEASES [J].

CUMIN, F ;

NISATO, D ;

GAGNOL, JP ;

CORVOL, P .

BIOCHEMISTRY, 1987, 26 (24) :7615-7621

[4] OPTIMIZATION AND INVIVO EVALUATIONS OF A SERIES OF SMALL, POTENT, AND SPECIFIC RENIN INHIBITORS CONTAINING A NOVEL LEU-VAL REPLACEMENT [J].

DELLARIA, JF ;

MAKI, RG ;

BOPP, BA ;

COHEN, J ;

KLEINERT, HD ;

LULY, JR ;

MERITS, I ;

PLATTNER, JJ ;

STEIN, HH .

JOURNAL OF MEDICINAL CHEMISTRY, 1987, 30 (11) :2137-2144

[5] DETERMINATION OF THE ANGIOTENSIN CONVERTING ENZYME-INHIBITOR BENAZEPRILAT IN PLASMA AND URINE BY AN ENZYMIC METHOD [J].

GRAF, P ;

FRUEH, F ;

SCHMID, K .

JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS, 1988, 425 (02) :353-361

[6] EXTRACTION PURIFICATION AND ASSAY OF HUMAN RENIN FREE OF ANGIOTENSINASE [J].

HAAS, E ;

GOLDBLATT, H ;

GIPSON, EC ;

LEWIS, LV .

CIRCULATION RESEARCH, 1966, 19 (04) :739-+

[7] NO EVIDENCE FOR PRODUCT INHIBITION OF RENIN-ANGIOTENSINOGEN REACTION IN RAT [J].

HACKENTHAL, E ;

HACKENTHAL, R ;

HOFBAUER, KG .

CIRCULATION RESEARCH, 1977, 41 (04) :R249-R254

[8] MONOCLONAL-ANTIBODIES TO HUMAN RENIN - PROPERTIES AND APPLICATIONS [J].

HEUSSER, CH ;

BEWS, JPA ;

ALKAN, SS ;

DIETRICH, FM ;

WOOD, JM ;

DEGASPARO, M ;

HOFBAUER, KG .

CLINICAL AND EXPERIMENTAL HYPERTENSION PART A-THEORY AND PRACTICE, 1987, 9 (8-9) :1259-1275

[9]

KLEINERT HD, 1988, J PHARMACOL EXP THER, V246, P975

[10]

MARSCHNER I, 1980, J CLIN CHEM CLIN BIO, V18, P105

← 1 2 →