INTERACTIONS OF THE NEUROTOXIC AMINE 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE WITH MONOAMINE OXIDASES

被引：91

作者：

SINGER, TP

SALACH, JI

CASTAGNOLI, N

TREVOR, A

机构：

[1] UNIV CALIF SAN FRANCISCO,DEPT PHARMACEUT CHEM,SAN FRANCISCO,CA 94143

[2] UNIV CALIF SAN FRANCISCO,DEPT PHARMACOL,SAN FRANCISCO,CA 94143

[3] VET ADM MED CTR,DIV MOLEC BIOL,SAN FRANCISCO,CA 94121

来源：

关键词：

D O I：

10.1042/bj2350785

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：785 / 789

页数：5

共 28 条

[1] BLASCHKO H, 1963, ENZYMES, V8, P337
[2] A PRIMATE MODEL OF PARKINSONISM - SELECTIVE DESTRUCTION OF DOPAMINERGIC-NEURONS IN THE PARS COMPACTA OF THE SUBSTANTIA NIGRA BY N-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE
BURNS, RS
CHIUEH, CC
MARKEY, SP
EBERT, MH
JACOBOWITZ, DM
KOPIN, IJ
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (14): : 4546 - 4550
[3] ETIOLOGY OF PARKINSONS-DISEASE
CALNE, DB
LANGSTON, JW
[J]. LANCET, 1983, 2 (8365) : 1457 - 1459
[4] POTENTIAL BIOACTIVATION PATHWAYS FOR THE NEUROTOXIN 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP)
CASTAGNOLI, N
CHIBA, K
TREVOR, AJ
[J]. LIFE SCIENCES, 1985, 36 (03) : 225 - 230
[5] METABOLISM OF THE NEUROTOXIC TERTIARY AMINE, MPTP, BY BRAIN MONOAMINE-OXIDASE
CHIBA, K
TREVOR, A
CASTAGNOLI, N
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1984, 120 (02) : 574 - 578
[6] ACTIVE UPTAKE OF MPP+, A METABOLITE OF MPTP, BY BRAIN SYNAPTOSOMES
CHIBA, K
TREVOR, AJ
CASTAGNOLI, N
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1985, 128 (03) : 1228 - 1232
[7] CHIBA K, 1985, DRUG METAB DISPOS, V13, P343
[8] FULLER RW, 1985, J PHARMACOL EXP THER, V232, P696
[9] GHISLA S, 1973, LIEBIGS ANN CHEM, P1388
[10] HEIKKILA RE, 1984, NATURE, V311, P467, DOI 10.1038/311467a0