POTENTIAL BIOACTIVATION PATHWAYS FOR THE NEUROTOXIN 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP)

被引：140

作者：

CASTAGNOLI, N

CHIBA, K

TREVOR, AJ

机构：

来源：

关键词：

D O I：

10.1016/0024-3205(85)90063-3

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

引用

页码：225 / 230

页数：6

共 12 条

[1] METABOLISM OF THE NEUROTOXIC TERTIARY AMINE, MPTP, BY BRAIN MONOAMINE-OXIDASE
CHIBA, K
TREVOR, A
CASTAGNOLI, N
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1984, 120 (02) : 574 - 578
[2] CHRONIC PARKINSONISM SECONDARY TO INTRAVENOUS-INJECTION OF MEPERIDINE ANALOGS
DAVIS, GC
WILLIAMS, AC
MARKEY, SP
EBERT, MH
CAINE, ED
REICHERT, CM
KOPIN, IJ
[J]. PSYCHIATRY RESEARCH, 1979, 1 (03) : 249 - 254
[3] GRAHAM DG, 1978, MOL PHARMACOL, V14, P633
[4] ALPHA-CYANATION OF TERTIARY-AMINES
GROUTAS, WC
ESSAWI, M
PORTOGHESE, PS
[J]. SYNTHETIC COMMUNICATIONS, 1980, 10 (07) : 495 - 502
[5] HEIKKILA RE, NATURE LOND
[6] CHRONIC PARKINSONISM IN HUMANS DUE TO A PRODUCT OF MEPERIDINE-ANALOG SYNTHESIS
LANGSTON, JW
BALLARD, P
TETRUD, JW
IRWIN, I
[J]. SCIENCE, 1983, 219 (4587) : 979 - 980
[7] PARGYLINE PREVENTS MPTP-INDUCED PARKINSONISM IN PRIMATES
LANGSTON, JW
IRWIN, I
LANGSTON, EB
FORNO, LS
[J]. SCIENCE, 1984, 225 (4669) : 1480 - 1482
[8] MARIETTA MP, 1979, J PHARMACOL EXP THER, V208, P271
[9] MARKEY SP, NATURE LOND
[10] Moore K.E., 1978, PSYCHOPHARMACOLOGY G, P221