EFFICIENT SYNTHESIS OF 4-THIO-D-RIBOFURANOSE AND SOME 4'-THIORIBONUCLEOSIDES

被引：46

作者：

BELLON, L ^{[1
]}

BARASCUT, JL ^{[1
]}

IMBACH, JL ^{[1
]}

机构：

[1] UNIV MONTPELLIER 2,CHIM BIOORGAN LAB,CNRS,UA 488,CASE 008,PL E BATAILLON,F-34095 MONTPELLIER 5,FRANCE

来源：

NUCLEOSIDES & NUCLEOTIDES | 1992年 / 11卷 / 08期

关键词：

D O I：

10.1080/07328319208021189

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A synthetic pathway to reach easily the 4-thio-D-ribofuranose is described. Some corresponding pyrimidine alpha and beta 4'-thioribonucleosides have been synthesized and evaluated as antiviral agents against various viruses.

引用

页码：1467 / 1479

页数：13

共 29 条

[21] Rideout J. L., 1983, NUCLEOSIDES NUCLEOTI
[22] RITCHIE R G S, 1973, Journal of the Chemical Society Chemical Communications, P686, DOI 10.1039/c39730000686
[23] SYNTHESIS AND BIOLOGICAL-ACTIVITY OF 2'-DEOXY-4'-THIOPYRIMIDINE NUCLEOSIDES
SECRIST, JA
TIWARI, KN
RIORDAN, JM
MONTGOMERY, JA
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1991, 34 (08) : 2361 - 2366
[24] SYNTHESIS AND ANTI-HIV ACTIVITY OF 4'-THIO-2',3'-DIDEOXYNUCLEOSIDES
SECRIST, JA
RIGGS, RM
TIWARI, KN
MONTGOMERY, JA
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1992, 35 (03) : 533 - 538
[25] SYNTHESIS OF PURINE AND PYRIMIDINE NUCLEOSIDES OF THIOPENTOSES
URBAS, B
WHISTLER, RL
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1966, 31 (03) : 813 - &
[26] SYNTHESIS OF O-METHYL DERIVATIVES OF 4-THIOPENTOFURANOSIDES AND 2,5-ANHYDROPENTOSES
VANES, T
[J]. CARBOHYDRATE RESEARCH, 1976, 46 (02) : 237 - 244
[27] WALKER RT, 1979, NATO ADV STUDY I A, V26
[28] 4-THIO-D-ARABINOFURANOSYLPYRIMIDINE NUCLEOSIDES
WHISTLER, RL
DONER, LW
NAYAK, UG
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1971, 36 (01) : 108 - &
[29] Whistler RL, 1977, ACS SYM SER, V39, P133

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