SYMMETRICAL STRUCTURE ALLOWING THE SELECTIVE MULTIPLE RELEASE OF A DEFINED QUANTITY OF PEPTIDE FROM A SINGLE BEAD OF POLYMERIC SUPPORT

被引：29

作者：

KOCIS, P ^{[1
]}

KRCHNAK, V ^{[1
]}

LEBL, M ^{[1
]}

机构：

[1] SELECTIDE CORP,1580 E HANLEY BLVD,TUCSON,AZ 85737

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 45期

关键词：

D O I：

10.1016/S0040-4039(00)79300-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A linker based on the combination of two molecules of iminodiacetic acid that allows for the release of peptide molecule from the polymeric bead in two equimolar portions in two distinct steps was designed and synthesized and its predicted properties were verified.

引用

页码：7251 / 7252

页数：2

共 7 条

[1] GAS-PHASE CLEAVAGE OF PEPTIDES FROM A SOLID SUPPORT WITH AMMONIA VAPOR - APPLICATION IN SIMULTANEOUS MULTIPLE PEPTIDE-SYNTHESIS [J].