RHO AS A REGULATOR OF THE CYTOSKELETON

被引：374

作者：

TAKAI, Y ^{[1
]}

SASAKI, T ^{[1
]}

TANAKA, K ^{[1
]}

NAKANISHI, H ^{[1
]}

机构：

[1] NATL INST PHYSIOL SCI,DEPT CELL PHYSIOL,OKAZAKI,AICHI 444,JAPAN

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1995年 / 20卷 / 06期

关键词：

D O I：

10.1016/S0968-0004(00)89022-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Many cell functions, including maintenance of morphology, aggregation, motility, membrane ruffling, smooth-muscle contraction, cytokinesis in mammals and bud formation in yeast, are regulated through the dynamic reorganization of actin filaments. Although it has long been known that Ca2+ is a hey regulator of the cytoskeleton, evidence is now accumulating that Rho, a Ras-related small GTP-binding protein, is another important regulator of these actin-dependent cell functions.

引用

页码：227 / 231

页数：5

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