TOTAL SYNTHESIS OF (+)-POLYOXIN-J

被引：30

作者：

DONDONI, A ^{[1
]}

JUNQUERA, F ^{[1
]}

MERCHAN, FL ^{[1
]}

MERINO, P ^{[1
]}

TEJERO, T ^{[1
]}

机构：

[1] UNIV ZARAGOZA,ICMA,DEPT QUIM ORGAN,ZARAGOZA,SPAIN

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1995年 / 20期

关键词：

D O I：

10.1039/c39950002127

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The antifungal antibiotic, polyoxin J 1, has been obtained (46.4%) by the coupling of a protected derivative of 5-O-carbamoylpolyoxamic acid 2 with thymine polyoxin C 3 which were prepared by a stereoselective aminohomologation strategy of sugar aldehydes (L-threose and dialdo-D-ribofuranose) employing nitrones 4 and 5 as their iminium derivatives and furan as a carboxylate group equivalent.

引用

页码：2127 / 2128

页数：2

共 17 条

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