TOTAL SYNTHESIS OF THYMINE POLYOXIN-C

被引：43

作者：

DONDONI, A ^{[1
]}

JUNQUERA, F ^{[1
]}

MERCHAN, FL ^{[1
]}

MERINO, P ^{[1
]}

TEJERO, T ^{[1
]}

机构：

[1] UNIV ZARAGOZA,CSIC,ICMA,DEPT QUIM ORGAN,E-50009 ZARAGOZA,SPAIN

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 50期

关键词：

D O I：

10.1016/S0040-4039(00)78564-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An expeditious synthesis of thymine polyoxin C in 6 steps (7.2% overall yield) bared on the stereocontrolled addition of 2-lithiofuran, a masked carboxylate group, to the N-benzyl nitrone derived from methyl 2,3-O-isopropylidene-dialdo-D-ribofuranoside, is described.

引用

页码：9439 / 9442

页数：4

共 16 条

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[3] ASYMMETRIC ALPHA-AMINO-ACID SYNTHESIS USING [3.3] REARRANGEMENT OF ALLYLIC TRIFLUOROACETIMIDATES - SYNTHESIS OF THYMINE POLYOXIN-C
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TEJERO, T
[J]. TETRAHEDRON LETTERS, 1993, 34 (34) : 5479 - 5482
[6] STEREOCONTROLLED ADDITION OF 2-LITHIOTHIAZOLE TO THE NITRONE DERIVED FROM D-GLYCERALDEHYDE ACETONIDE - A REVISION AND EXTENSION
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[7] STEREOSELECTIVE AMINOHOMOLOGATION OF CHIRAL ALPHA-ALKOXY ALDEHYDES VIA THIAZOLE ADDITION TO NITRONES - APPLICATION TO THE SYNTHESIS OF N-ACETYL-D-MANNOSAMINE
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[8] DONDONI A, 1993, SYNLETT, P78
[9] DONDONI A, 1994, IN PRESS SYNTH COMMU
[10] GLYCOSYL ALPHA-AMINO-ACIDS VIA STEREOCONTROLLED BUILDUP OF A PENALDIC ACID EQUIVALENT - A NOVEL SYNTHETIC APPROACH TO THE NUCLEOSIDIC COMPONENT OF THE POLYOXINS AND RELATED SUBSTANCES
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