共 21 条
[21]
1993, HUM MOL GENET, V3, P621
IDENTIFICATION AND CHROMOSOMAL MAPPING OF A 3RD MOUSE RUNT-LIKE LOCUS
被引：13
作者：
CALABI, F
RHODES, M
WILLIAMSON, P
BOYD, Y
机构：
[1] HGMP RESOURCE CTR,HINXTON CB10 1RQ,CAMBS,ENGLAND
[2] MRC,RADIOBIOL UNIT,DIDCOT OX11 0RD,OXON,ENGLAND
来源：
基金：
英国医学研究理事会;
关键词：
D O I：
10.1016/0888-7543(95)80184-N
中图分类号：
Q81 [生物工程学（生物技术）];
Q93 [微生物学];
学科分类号：
071005 ;
0836 ;
090102 ;
100705 ;
摘要：
The Drosophila runt gene, which controls early events in embryogenesis, has been shown to have homologues in human and mouse. The human gene on 21q22 is involved in the t(8;21) associated with acute myeloid leukemia. Two mouse runt-like loci encoding DNA-binding proteins have been identified. We report here the isolation and partial sequence of a molecular clone of a third mouse runt-like locus. By using a panel of somatic cell hybrids and interspecific backcross mice, we map the novel locus to the telomeric region Of mouse chromosome 4. (C) 1995 Academic Press, Inc.
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页码：607 / 610
页数：4
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