QUANTITATIVE LIQUID-CHROMATOGRAPHIC THERMOSPRAY-TANDEM MASS-SPECTROMETRIC ANALYSIS OF SOME ANALGESICS AND TRANQUILIZERS OF THE METHADONE, BUTYROPHENONE OR DIPHENYLBUTYLPIPERIDINE GROUPS IN WHOLE-BLOOD

被引：10

作者：

VERWEIJ, AMA ^{[1
]}

HORDIJK, ML ^{[1
]}

LIPMAN, PJL ^{[1
]}

机构：

[1] MINIST JUSTICE,FORENS SCI LAB,DEPT TOXICOL,2288 GD RIJSWIJK,NETHERLANDS

来源：

JOURNAL OF ANALYTICAL TOXICOLOGY | 1995年 / 19卷 / 02期

关键词：

D O I：

10.1093/jat/19.2.65

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The results of a liquid chromatographic-mass spectrometric method for the quantitative determination of some medicaments of the methadone, butyrophenone, or diphenylbutylpiperidine groups in whole blood are presented. The method includes an extraction procedure with Bond Elut columns. The liquid chromatograph is connected to a mass spectrometer by a thermospray interface, and to obtain as high a sensitivity and selectivity as possible, a selected reaction monitoring mass spectrometric technique in the daughter ion mode is applied. © 1995 Oxford University Press.

引用

页码：65 / 68

页数：4

共 7 条

[1]

HEEREMANS CEM, 1990, THESIS U LEIDEN LEID

[2]

MOFFAT AC, 1986, CLARKES ISOLATION ID, P378

[3]

NIESSEN WMA, 1992, LIQUID CHROMATOGRAPH, P157

[4] COMPARISON OF MASS-SPECTROMETRIC TECHNIQUES FOR THE ANALYSIS OF TRACE AMOUNTS OF 1-METHYLAMINOANTHRAQUINONE, USED AS SMOKE DYE IN EXPLODING MONEY SUITCASES [J].

VERWEIJ, AMA ;

LIPMAN, PJL .

JOURNAL OF CHROMATOGRAPHY A, 1993, 653 (02) :359-362

[5] QUANTITATIVE LIQUID-CHROMATOGRAPHY, THERMOSPRAY TANDEM MASS-SPECTROMETRY (LC TSP MS MS) ANALYSIS OF SOME THERMOLABILE BENZODIAZEPINES IN WHOLE-BLOOD [J].

VERWEIJ, AMA ;

LIPMAN, PJL ;

ZWEIPFENNING, PGM .

FORENSIC SCIENCE INTERNATIONAL, 1992, 54 (01) :67-74

[6]

WINDHOLZ M, 1986, MERCK INDEX

[7]

Yinon J, 1991, FORENSIC SCI PROG, V5, P1

← 1 →