RECENT DEVELOPMENT OF MONOFLUORINATION AND DIFLUORINATION

被引：26

作者：

UNEYAMA, K

机构：

[1] Department of Applied Chemistry, Faculty of Engineering, Okayama University

来源：

JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN | 1993年 / 51卷 / 03期

关键词：

FLUORINATION; DIFLUORINATION;

D O I：

10.5059/yukigoseikyokaishi.51.232

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Monofluorination is mainly classified into two types of reactions; electrophilic and nucleophilic fluorinations. Preparations of monofluorinated compounds by the use of monofluorocarbene intermediates and monofluorinated building blocks are also summarized. Recent development of difluorination via difluorocarbene, substituted difluoromethyl radicals, transformations of carbonyl and methylene groups to difluoromethylene group along with utilization of the difluoromethylated building blocks has been reviewed.

引用

收藏

页码：232 / 246

页数：15

相关论文

共 258 条

[1]

aDe Meio G. V., 1990, J CHEM SOC CHEM COMM, P1065

[2] ETHYL PHENYLSULFINYL FLUOROACETATE, A NEW AND VERSATILE REAGENT FOR THE PREPARATION OF ALPHA-FLUORO-ALPHA,BETA-UNSATURATED CARBOXYLIC-ACID ESTERS [J].

ALLMENDINGER, T .

TETRAHEDRON, 1991, 47 (27) :4905-4914

[3] FLUOROOLEFIN DIPEPTIDE ISOSTERES .2. ENANTIOSELECTIVE SYNTHESIS OF BOTH ANTIPODES OF THE PHE-GLY DIPEPTIDE MIMIC [J].

ALLMENDINGER, T ;

FELDER, E ;

HUNGERBUHLER, E .

TETRAHEDRON LETTERS, 1990, 31 (50) :7301-7304

[4] GENERAL-SYNTHESIS OF POLYFUNCTIONALIZED FLUOROMETHYLENEKETONE RETROAMIDES AS POTENTIAL INHIBITORS OF THROMBIN [J].

ALTENBURGER, JM ;

SCHIRLIN, D .

TETRAHEDRON LETTERS, 1991, 32 (49) :7255-7258

[5]

ALVERNHE G, 1987, SYNTHESIS-STUTTGART, P562

[6] SYNTHESIS OF FLUORO NITRO ETHERS BY MICHAEL ADDITION-REACTIONS TO ACTIVATED BETA,BETA-DIFLUOROOLEFINS [J].

ARCHIBALD, TG ;

BAUM, K .

JOURNAL OF ORGANIC CHEMISTRY, 1990, 55 (11) :3562-3565

[7] SYNTHESIS OF THE 2 ENANTIOMERS OF 1-CHLORO-1,1-DIFLUORO-3-(PARA-TOLYLSULPHONYL)PROPAN-2-OL BY MICROBIAL REDUCTION OF THE PARENT PROPANONE AND TRANSFORMATION INTO 3,3-DIFLUOROTETRAHYDROFURAN DERIVATIVES [J].

ARNONE, A ;

BERNARDI, R ;

BRAVO, P ;

CARDILLO, R ;

GHIRINGHELLI, D ;

CAVICCHIO, G .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1991, (08) :1887-1891

[8] PREPARATION OF ALPHA-SUBSTITUTED S-PHENYLTHIO ESTERS FROM 2-NITRO-2-PHENYLTHIO OXIRANES [J].

ASHWELL, M ;

JACKSON, RFW ;

KIRK, JM .

TETRAHEDRON, 1990, 46 (21) :7429-7442

[9] SYNTHESIS OF GEM-DIFLUOROCYCLOPROPANES IN A PHASE-TRANSFER CATALYZED SYSTEM [J].

BALCERZAK, P ;

FEDORYNSKI, M ;

JONCZYK, A .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1991, (12) :826-827

[10] N-HALOGENO COMPOUNDS .13. N-FLUOROQUINUCLIDINIUM SALTS - SYNTHESIS AND USE AS ELECTROPHILIC FLUORINATING AGENTS [J].

BANKS, RE ;

SHARIF, I .

JOURNAL OF FLUORINE CHEMISTRY, 1991, 55 (02) :207-214

← 1 2 3 4 5 6 7 8 9 10 →