REGIOSELECTIVE AND ENANTIOSELECTIVE ESTERIFICATIONS OF POLYOXYGENATED COMPOUNDS CATALYZED BY LIPASES

被引：29

作者：

HERRADON, B ^{[1
]}

CUETO, S ^{[1
]}

MORCUENDE, A ^{[1
]}

VALVERDE, S ^{[1
]}

机构：

[1] SWISS FED INST TECHNOL, TECH CHEM LAB, CH-8092 ZURICH, SWITZERLAND

来源：

TETRAHEDRON-ASYMMETRY | 1993年 / 4卷 / 05期

关键词：

D O I：

10.1016/S0957-4166(00)80123-8

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The lipase catalyzed esterifications of derivatives of propane-1,2,3-triol and butane-1,2,4-triol in organic solvents have been studied. The influence of several factors (lipase source, organic solvent, additives and structural variations in die substrates) on the selectivity have been investigated. Good levels of regio- and enantioselectivity have been achieved, providing practical methods for the synthesis of these chiral building blocks.

引用

页码：845 / 864

页数：20

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