TOTAL SYNTHESES OF PHLEICHROME, CALPHOSTIN-A, AND CALPHOSTIN-D - UNUSUAL STEREOSELECTIVE AND STEREOSPECIFIC REACTIONS IN THE SYNTHESIS OF PERYLENEQUINONES

被引：53

作者：

BROKA, CA

机构：

[1] Syntex Research, Institute of Bio-Organic Chemistry, Palo Alto, CA 94304

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 07期

关键词：

D O I：

10.1016/S0040-4039(00)92105-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This report describes the total synthesis of phleichrome, calphostin A and calphostin D - three protein kinase C inhibitory perylenequinones. The present route affords the targets in enantiomerically pure form and represents the first successful approach to this biologically important class of metabolites.

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页码：859 / 862

页数：4

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