The epigenetic machinery controlling transgenerational systemic acquired resistance

被引:108
作者
Luna, Estrella [1 ,2 ]
Ton, Jurriaan [1 ]
机构
[1] Univ Sheffield, Dept Anim & Plant Sci, Sheffield, S Yorkshire, England
[2] Univ Lancaster, Lancaster Environm Ctr, Lancaster, England
基金
英国生物技术与生命科学研究理事会;
关键词
transgenerational systemic acquired resistance; RNA-directed DNA methylation; chromatin remodeling; DNA methylation; priming of defense;
D O I
10.4161/psb.20155
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Progeny from diseased Arabidopsis shows enhanced resistance, which is associated with priming of defense genes.(1) This transgenerational systemic acquired resistance (SAR) is effective against biotrophic pathogens, such as the downy mildew pathogen Hyaloperonospora arabidopsidis. In this study, we have examined mutants in RNA-directed DNA methylation (RdDM) for transgenerational SAR. Our analysis suggests that transgenerational SAR is regulated by the RdDM pathway and transmitted by hypomethylation at CpNpG sites.
引用
收藏
页码:615 / 618
页数:4
相关论文
共 26 条
[1]   ARGONAUTE4 is required for resistance to Pseudomonas syringae in Arabidopsis [J].
Agorio, Astrid ;
Vera, Pablo .
PLANT CELL, 2007, 19 (11) :3778-3790
[2]   Natural variation in priming of basal resistance: from evolutionary origin to agricultural exploitation [J].
Ahmad, Shakoor ;
Gordon-Weeks, Ruth ;
Pickett, John ;
Ton, Jurriaan .
MOLECULAR PLANT PATHOLOGY, 2010, 11 (06) :817-827
[3]   RNAi, DRD1, and histone methylation actively target developmentally important non-CG DNA methylation in Arabidopsis [J].
Chan, Simon W. -L. ;
Henderson, Ian R. ;
Zhang, Xiaoyu ;
Shah, Govind ;
Chien, Jason S. -C. ;
Jacobsen, Steven E. .
PLOS GENETICS, 2006, 2 (06) :791-797
[4]   Priming:: Getting ready for battle [J].
Conrath, Uwe ;
Beckers, Gerold J. M. ;
Flors, Victor ;
Garcia-Agustin, Pilar ;
Jakab, Gabor ;
Mauch, Felix ;
Newman, Mari-Anne ;
Pieterse, Corne M. J. ;
Poinssot, Benoit ;
Pozo, Maria J. ;
Pugin, Alain ;
Schaffrath, Ulrich ;
Ton, Jurriaan ;
Wendehenne, David ;
Zimmerli, Laurent ;
Mauch-Mani, Brigitte .
MOLECULAR PLANT-MICROBE INTERACTIONS, 2006, 19 (10) :1062-1071
[5]   Molecular aspects of defence priming [J].
Conrath, Uwe .
TRENDS IN PLANT SCIENCE, 2011, 16 (10) :524-531
[6]   Multisubunit RNA polymerases IV and V: purveyors of non-coding RNA for plant gene silencing [J].
Haag, Jeremy R. ;
Pikaard, Craig S. .
NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2011, 12 (08) :483-492
[7]   The Arabidopsis RNA-Directed DNA Methylation Argonautes Functionally Diverge Based on Their Expression and Interaction with Target Loci [J].
Havecker, Ericka R. ;
Wallbridge, Laura M. ;
Hardcastle, Thomas J. ;
Bush, Maxwell S. ;
Kelly, Krystyna A. ;
Dunn, Ruth M. ;
Schwach, Frank ;
Doonan, John H. ;
Baulcombe, David C. .
PLANT CELL, 2010, 22 (02) :321-334
[8]   Tandem repeats upstream of the Arabidopsis endogene SDC recruit non-CG DNA methylation and initiate siRNA spreading [J].
Henderson, Ian R. ;
Jacobsen, Steven E. .
GENES & DEVELOPMENT, 2008, 22 (12) :1597-1606
[9]   Dissecting Arabidopsis thaliana DICER function in small RNA processing, gene silencing and DNA methylation patterning [J].
Henderson, Ian R. ;
Zhang, Xiaoyu ;
Lu, Cheng ;
Johnson, Lianna ;
Meyers, Blake C. ;
Green, Pamela J. ;
Jacobsen, Steven E. .
NATURE GENETICS, 2006, 38 (06) :721-725
[10]   Control of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase [J].
Jackson, JP ;
Lindroth, AM ;
Cao, XF ;
Jacobsen, SE .
NATURE, 2002, 416 (6880) :556-560