FREEZING TRANSITION OF RANDOM HETEROPOLYMERS CONSISTING OF AN ARBITRARY SET OF MONOMERS

被引：45

作者：

PANDE, VS ^{[1
]}

GROSBERG, AY ^{[1
]}

TANAKA, T ^{[1
]}

机构：

[1] MIT,CTR MAT SCI & ENGN,CAMBRIDGE,MA 02139

来源：

PHYSICAL REVIEW E | 1995年 / 51卷 / 04期

关键词：

D O I：

10.1103/PhysRevE.51.3381

中图分类号：

O35 [流体力学]; O53 [等离子体物理学];

学科分类号：

070204 ; 080103 ; 080704 ;

摘要：

Mean field replica theory is employed to analyze the freezing transition of random heteropolymers comprised of an arbitrary number (q) of types of monomers. Our formalism assumes that interactions are short range and heterogeneity comes only from pairwise interactions, which are defined by an arbitrary q×q matrix. We show that, in general, there exists a freezing transition from a random globule, in which the thermodynamic equilibrium is comprised of an essentially infinite number polymer conformations, to a frozen globule, in which equilibrium ensemble is dominated by one or very few conformations. We also examine some special cases of interaction matrices to analyze the relationship between the freezing transition and the nature of the interactions involved. © 1995 The American Physical Society.

引用

页码：3381 / 3392

页数：12

共 20 条

[11] ESTIMATION OF EFFECTIVE INTERRESIDUE CONTACT ENERGIES FROM PROTEIN CRYSTAL-STRUCTURES - QUASI-CHEMICAL APPROXIMATION [J].