TUMOR-SUPPRESSOR GENES - PROSPECTS FOR CANCER THERAPIES - SHOULD THERAPY BE AIMED AT RESTORING NORMAL PHENOTYPE TO CANCER-CELLS OR AT ELIMINATING THE CELLS ALTOGETHER

被引：7

作者：

BERTELSEN, AH

BEAUDRY, GA

STOLLER, TJ

TROTTA, PP

SHERMAN, MI

机构：

来源：

BIO-TECHNOLOGY | 1995年 / 13卷 / 02期

关键词：

D O I：

10.1038/nbt0295-127

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

引用

页码：127 / 131

页数：5

共 121 条

[51] HARPER JW, 1993, CELL, V75, P805
[52] SUPPRESSION OF MALIGNANCY BY CELL FUSION
HARRIS, H
MILLER, OJ
KLEIN, G
WORST, P
TACHIBANA, T
[J]. NATURE, 1969, 223 (5204) : 363 - +
[53] HEDNEK L, 1992, COLD SPRING HARB SYM, V57, P345
[54] P53 MUTATIONS IN HUMAN CANCERS
HOLLSTEIN, M
SIDRANSKY, D
VOGELSTEIN, B
HARRIS, CC
[J]. SCIENCE, 1991, 253 (5015) : 49 - 53
[55] SUPPRESSION OF THE NEOPLASTIC PHENOTYPE BY REPLACEMENT OF THE RB GENE IN HUMAN CANCER-CELLS
HUANG, HJS
YEE, JK
SHEW, JY
CHEN, PL
BOOKSTEIN, R
FRIEDMANN, T
LEE, EYHP
LEE, WH
[J]. SCIENCE, 1988, 242 (4885) : 1563 - 1566
[56] COOPERATION BETWEEN ONCOGENES
HUNTER, T
[J]. CELL, 1991, 64 (02) : 249 - 270
[57] ACTIVATION OF THE CRYPTIC DNA-BINDING FUNCTION OF MUTANT FORMS OF P53
HUPP, TR
MEEK, DW
MIDGLEY, CA
LANE, DP
[J]. NUCLEIC ACIDS RESEARCH, 1993, 21 (14) : 3167 - 3174
[58] A CELL-CYCLE REGULATOR POTENTIALLY INVOLVED IN GENESIS OF MANY TUMOR TYPES
KAMB, A
GRUIS, NA
WEAVERFELDHAUS, J
LIU, QY
HARSHMAN, K
TAVTIGIAN, SV
STOCKERT, E
DAY, RS
JOHNSON, BE
SKOLNICK, MH
[J]. SCIENCE, 1994, 264 (5157) : 436 - 440
[59] A MAMMALIAN-CELL CYCLE CHECKPOINT PATHWAY UTILIZING P53 AND GADD45 IS DEFECTIVE IN ATAXIA-TELANGIECTASIA
KASTAN, MB
ZHAN, QM
ELDEIRY, WS
CARRIER, F
JACKS, T
WALSH, WV
PLUNKETT, BS
VOGELSTEIN, B
FORNACE, AJ
[J]. CELL, 1992, 71 (04) : 587 - 597
[60] KASTAN MB, 1991, CANCER RES, V51, P6304