NUCLEIC-ACID RELATED-COMPOUNDS .47. SYNTHESIS AND BIOLOGICAL-ACTIVITIES OF PYRIMIDINE AND PURINE ACYCLIC NUCLEOSIDE ANALOGS

被引：63

作者：

ROBINS, MJ ^{[1
]}

HATFIELD, PW ^{[1
]}

BALZARINI, J ^{[1
]}

DECLERCQ, E ^{[1
]}

机构：

[1] CATHOLIC UNIV LEUVEN, REGA INST MED RES, B-3000 LOUVAIN, BELGIUM

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1984年 / 27卷 / 11期

关键词：

D O I：

10.1021/jm00377a018

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1486 / 1492

页数：7

共 47 条

[1] SYNTHESIS OF PYRIMIDINE ACYCLONUCLEOSIDES [J].

ABRAMS, HM ;

HO, L ;

CHU, SH .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1981, 18 (05) :947-951

[2] ACTIVATION BY THYMIDINE KINASE AND POTENT ANTIHERPETIC ACTIVITY OF 2'-NOR-2'-DEOXYGUANOSINE (2'NDG) [J].

ASHTON, WT ;

KARKAS, JD ;

FIELD, AK ;

TOLMAN, RL .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1982, 108 (04) :1716-1721

[3] A DIRECT METHOD FOR THE PREPARATION OF 2-HYDROXYETHOXYMETHYL DERIVATIVES OF GUANINE, ADENINE, AND CYTOSINE [J].

BARRIO, JR ;

BRYANT, JD ;

KEYSER, GE .

JOURNAL OF MEDICINAL CHEMISTRY, 1980, 23 (05) :572-574

[4] ACYCLIC NUCLEOSIDE ANALOGS - SYNTHESIS OF OPEN-RING RIBOSIDE OR DEOXYRIBOSIDE ANALOGS LACKING C(3') OR THE C(3')-C(4') BOND [J].

BRYANT, JD ;

KEYSER, GE ;

BARRIO, JR .

JOURNAL OF ORGANIC CHEMISTRY, 1979, 44 (21) :3733-3734

[5] ACTIVITY INVITRO AGAINST HERPES-VIRUS OF 9-(2-HYDROXYETHOXYMETHYL)GUANINE (ACYCLOGUANOSINE), A NEW ANTI-VIRAL AGENT [J].

COLLINS, P ;

BAUER, DJ .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1979, 5 (04) :431-436

[6] (S)-9-(2,3-DIHYDROXYPROPYL)ADENINE - ALIPHATIC NUCLEOSIDE ANALOG WITH BROAD-SPECTRUM ANTI-VIRAL ACTIVITY [J].

DECLERCQ, E ;

DESCAMPS, J ;

DESOMER, P .

SCIENCE, 1978, 200 (4341) :563-565

[7] COMPARATIVE EFFICACY OF ANTI-HERPES DRUGS IN DIFFERENT CELL-LINES [J].

DECLERCQ, E .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1982, 21 (04) :661-663

[8] COMPARATIVE EFFICACY OF ANTIHERPES DRUGS AGAINST DIFFERENT STRAINS OF HERPES-SIMPLEX VIRUS [J].

DECLERCQ, E ;

DESCAMPS, J ;

VERHELST, G ;

WALKER, RT ;

JONES, AS ;

TORRENCE, PF ;

SHUGAR, D .

JOURNAL OF INFECTIOUS DISEASES, 1980, 141 (05) :563-574

[9] ANTI-VIRAL ACTIVITY OF ALIPHATIC NUCLEOSIDE ANALOGS - STRUCTURE-FUNCTION RELATIONSHIP [J].

DECLERCQ, E ;

HOLY, A .

JOURNAL OF MEDICINAL CHEMISTRY, 1979, 22 (05) :510-513

[10]

DECLERCQ E, 1979, P NATL ACAD SCI USA, V76, P2947, DOI 10.1073/pnas.76.6.2947

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