SYNTHESIS OF A WATER-SOLUBLE O-CARBABORANE BEARING A URACIL MOIETY VIA A PALLADIUM-CATALYZED REACTION UNDER ESSENTIALLY NEUTRAL CONDITIONS

被引：40

作者：

NEMOTO, H

CAI, JP

YAMAMOTO, Y

机构：

[1] TOHOKU UNIV,FAC SCI,DEPT CHEM,SENDAI,MIYAGI 980,JAPAN

[2] OKAZAKI INST MOLEC SCI,DEPT APPL MOLEC SCI,OKAZAKI,AICHI 444,JAPAN

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1994年 / 05期

关键词：

D O I：

10.1039/c39940000577

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A water-soluble o-carbaborane bearing a uracil moiety 10 has been synthesized via a palladium-catalysed reaction under essentially neutral conditions.

引用

页码：577 / 578

页数：2

共 13 条

[1] SYNTHESIS OF A CARBORANYL NUCLEOSIDE FOR POTENTIAL USE IN NEUTRON-CAPTURE THERAPY OF CANCER [J].

ANISUZZAMAN, AKM ;

ALAM, F ;

SOLOWAY, AH .

POLYHEDRON, 1990, 9 (06) :891-892

[2]

HATANAKA H, 1992, PROGRESS IN NEUTRON CAPTURE THERAPY FOR CANCER, P561

[3] THE ROLE OF CHEMISTRY IN THE DEVELOPMENT OF BORON NEUTRON-CAPTURE THERAPY OF CANCER [J].

HAWTHORNE, MF .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1993, 32 (07) :950-984

[4] SYNTHESIS OF TETRAKIS-CARBORANE-CARBOXYLATE ESTERS OF 2,4-BIS-(ALPHA,BETA-DIHYDROXYETHYL)-DEUTEROPORPHYRIN-IX [J].

KAHL, SB ;

KOO, MS .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1990, (24) :1769-1771

[5]

KETS H, 1990, TETRAHEDRON LETT, V31, P4003

[6]

MAURER JL, 1990, J ORG CHEM, V55, P833

[7] THE 1ST ALKYLATION OF ORTHO-CARBORANES UNDER ESSENTIALLY NEUTRAL CONDITIONS - APPLICATION TO THE SYNTHESIS OF B-10 CARRIERS [J].

NEMOTO, H ;

RONG, F ;

YAMAMOTO, Y .

JOURNAL OF ORGANIC CHEMISTRY, 1990, 55 (25) :6065-6066

[8] POLYOLS OF A CASCADE TYPE AS A WATER-SOLUBILIZING ELEMENT OF CARBORANE DERIVATIVES FOR BORON NEUTRON-CAPTURE THERAPY [J].

NEMOTO, H ;

WILSON, JG ;

NAKAMURA, H ;

YAMAMOTO, Y .

JOURNAL OF ORGANIC CHEMISTRY, 1992, 57 (02) :435-435

[9] SYNTHESIS OF 5-(DIHYDROXYBORYL)-2'-DEOXYURIDINE AND RELATED BORON-CONTAINING PYRIMIDINES [J].

SCHINAZI, RF ;

PRUSOFF, WH .

JOURNAL OF ORGANIC CHEMISTRY, 1985, 50 (06) :841-847

[10]

TAKAGAKI M, COMMUNICATION

← 1 2 →