SINGLE-DOSE QUINIDINE TREATMENT INHIBITS METOPROLOL OXIDATION IN EXTENSIVE METABOLIZERS

被引：107

作者：

LEEMANN, T

DAYER, P

MEYER, UA

机构：

[1] UNIV GENEVA,HOP CANTONAL,DEPT MED,CLIN PHARMACOL UNIT,CH-1211 GENEVA 4,SWITZERLAND

[2] UNIV BASEL,BIOCTR,DEPT PHARMACOL,CH-4051 BASEL,SWITZERLAND

来源：

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY | 1986年 / 29卷 / 06期

关键词：

D O I：

10.1007/BF00615971

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：739 / 741

页数：3

共 17 条

[1] NORTRIPTYLINE AND ANTIPYRINE CLEARANCE IN RELATION TO DEBRISOQUINE HYDROXYLATION IN MAN [J].

BERTILSSON, L ;

EICHELBAUM, M ;

MELLSTROM, B ;

SAWE, J ;

SCHULZ, HU ;

SJOQVIST, F .

LIFE SCIENCES, 1980, 27 (18) :1673-1677

[2]

COOPER RG, 1984, LANCET, V2, P227

[3] CHARACTERIZATION OF A COMMON GENETIC-DEFECT OF CYTOCHROME-P-450 FUNCTION (DEBRISOQUINE-SPARTEINE TYPE POLYMORPHISM) - INCREASED MICHAELIS CONSTANT (KM) AND LOSS OF STEREOSELECTIVITY OF BUFURALOL 1'-HYDROXYLATION IN POOR METABOLIZERS [J].

DAYER, P ;

GASSER, R ;

GUT, J ;

KRONBACH, T ;

ROBERTZ, GM ;

EICHELBAUM, M ;

MEYER, UA .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1984, 125 (01) :374-380

[4] INTERINDIVIDUAL VARIATION OF BETA-ADRENOCEPTOR BLOCKING-DRUGS, PLASMA-CONCENTRATION AND EFFECT - INFLUENCE OF GENETIC STATUS ON BEHAVIOR OF ATENOLOL, BOPINDOLOL AND METOPROLOL [J].

DAYER, P ;

LEEMANN, T ;

MARMY, A ;

ROSENTHALER, J .

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1985, 28 (02) :149-153

[5] THE GENETIC-CONTROL OF BUFURALOL METABOLISM IN MAN [J].

DAYER, P ;

BALANT, L ;

COURVOISIER, F ;

KUPFER, A ;

KUBLI, A ;

GORGIA, A ;

FABRE, J .

EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS, 1982, 7 (01) :73-77

[6]

DENGLER HJ, 1977, ARZNEIMITTEL-FORSCH, V27-2, P1836

[7] CHARACTERIZATION OF A HUMAN-LIVER CYTOCHROME-P-450 INVOLVED IN THE OXIDATION OF DEBRISOQUINE AND OTHER DRUGS BY USING ANTIBODIES RAISED TO THE ANALOGOUS RAT ENZYME [J].

DISTLERATH, LM ;

GUENGERICH, FP .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (23) :7348-7352

[8] DEBRISOQUINE-TYPE POLYMORPHISM OF DRUG OXIDATION - PURIFICATION FROM HUMAN-LIVER OF A CYTOCHROME-P450 ISOZYME WITH HIGH-ACTIVITY FOR BUFURALOL HYDROXYLATION [J].

GUT, J ;

GASSER, R ;

DAYER, P ;

KRONBACH, T ;

CATIN, T ;

MEYER, UA .

FEBS LETTERS, 1984, 173 (02) :287-290

[9] QUINIDINE-INDUCED RISE IN AJMALINE PLASMA-CONCENTRATION [J].

HORI, R ;

OKUMURA, K ;

INUI, KI ;

YASUHARA, M ;

YAMADA, K ;

SAKURAI, T ;

KAWAI, C .

JOURNAL OF PHARMACY AND PHARMACOLOGY, 1984, 36 (03) :202-204

[10]

IDLE JR, 1984, 2ND P WORLD C CLIN P, P148

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