LIPOSOMES CONTAINING AMPHIPHILES PREPARED BY USING A LIPOPHILIC CHAIN TRANSFER REAGENT - RESPONSIVENESS TO EXTERNAL STIMULI

被引：33

作者：

KITANO, H

MAEDA, Y

TAKEUCHI, S

IEDA, K

AIZU, Y

机构：

[1] TOYAMA UNIV,FAC EDUC,TOYAMA 930,JAPAN

[2] KYOTO UNIV,DEPT POLYMER CHEM,KYOTO 60601,JAPAN

来源：

LANGMUIR | 1994年 / 10卷 / 02期

关键词：

D O I：

10.1021/la00014a012

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A lipophilic chain transfer reagent was prepared by coupling of N,N-dioctadecylamine with 3-mercaptopropionic acid, and telomerization of acrylic acid (product, DODA-S-PAA) or N-isopropylacrylamide (product, DODA-S-PIPA) was carried out by using the chain transfer reagent. The amphiphiles obtained formed stable liposomes with lecithin (L-alpha-dimyristoylphosphatidylcholine or L-alpha-dipalmitoylphosphatidylcholine), and the liposomes showed a pH-responsive (DODA-S-PAA) or temperature-responsive (DODA-S-PIPA) release of fluorophore from inner water pool. The lipophilic chain transfer reagent was useful to prepare amphiphiles with various functionalities.

引用

页码：403 / 406

页数：4

共 20 条

[1] APPARENT MOLAR HEAT-CAPACITIES OF PHOSPHOLIPIDS IN AQUEOUS DISPERSION - EFFECTS OF CHAIN-LENGTH AND HEAD GROUP-STRUCTURE [J].