A NEW STEREOSELECTIVE SYNTHESIS OF CHIRAL TETRAHYDROTHIOPYRANS AND THEIR CORRESPONDING SULFOXIDES

被引：25

作者：

HACHEM, A

TOUPET, L

GREE, R

机构：

[1] ECOLE NATL SUPER CHIM RENNES,CNRS,SYNTH & ACTIVAT BIOMOLEC LAB,F-35700 RENNES,FRANCE

[2] UNIV RENNES,CNRS,MAT CONDENSEE & MAT GRP,F-35042 RENNES,FRANCE

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 11期

关键词：

D O I：

10.1016/0040-4039(95)00139-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new stereoselective synthesis of chiral tetrahydrothiopyrans as been achieved based upon the intramolecular trapping of pentadienyl cations complexed to Fe(CO)(3) By sulfur nucleophiles. Oxidation of these heterocycles with Oxone(R) is compatible,with the organometallic moiety and leads in good diastereoselectivity to the corresponding sulfoxides.

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页码：1849 / 1852

页数：4

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