SYNTHESIS OF ANTIVIRAL NUCLEOSIDES FROM CROTONALDEHYDE .3. TOTAL SYNTHESIS OF DIDEHYDRODIDEOXYTHYMIDINE (D4T)

被引：13

作者：

JUNG, ME

GARDINER, JM

机构：

[1] Department of Chemistry and Biochemistry, University of California Los Angeles, Los Angeles

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 27期

基金：

英国惠康基金; 美国国家卫生研究院;

关键词：

D O I：

10.1016/S0040-4039(00)74799-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The total synthesis of the antiviral agent d4T 3 from the epoxyalcohol 2, itself derived from crotonaldehyde 1, in 6 steps and 18% overall yield is described.

引用

页码：3841 / 3844

页数：4

共 28 条

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