METABOLISM OF THE NEUROTOXIN IN MPTP BY HUMAN-LIVER MONOAMINE OXIDASE-B

被引：72

作者：

FRITZ, RR

ABELL, CW

PATEL, NT

GESSNER, W

BROSSI, A

机构：

[1] UNIV TEXAS, MED BRANCH, DEPT HUMAN BIOL CHEM & GENET, DIV BIOCHEM, GALVESTON, TX 77550 USA

[2] NIADDKD, CHEM LAB, BETHESDA, MD 20205 USA

来源：

FEBS LETTERS | 1985年 / 186卷 / 02期

关键词：

D O I：

10.1016/0014-5793(85)80713-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：224 / 228

页数：5

共 22 条

[1] POTENTIAL BIOACTIVATION PATHWAYS FOR THE NEUROTOXIN 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP) [J].

CASTAGNOLI, N ;

CHIBA, K ;

TREVOR, AJ .

LIFE SCIENCES, 1985, 36 (03) :225-230

[2] METABOLISM OF THE NEUROTOXIC TERTIARY AMINE, MPTP, BY BRAIN MONOAMINE-OXIDASE [J].

CHIBA, K ;

TREVOR, A ;

CASTAGNOLI, N .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1984, 120 (02) :574-578

[3] STUDIES ON THE MECHANISM OF ACTION OF 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP) [J].

COHEN, G ;

MYTILINEOU, C .

LIFE SCIENCES, 1985, 36 (03) :237-242

[4]

DENNEY RM, 1982, MOL PHARMACOL, V22, P500

[5]

DENNEY RM, 1983, MOL PHARMACOL, V24, P60

[6] HUMAN-LIVER MAO-A AND MAO-B SEPARATED BY IMMUNOAFFINITY CHROMATOGRAPHY WITH MAO-B-SPECIFIC MONOCLONAL-ANTIBODY [J].

DENNEY, RM ;

FRITZ, RR ;

PATEL, NT ;

ABELL, CW .

SCIENCE, 1982, 215 (4538) :1400-1403

[7] CENTRAL AND PERIPHERAL CATECHOLAMINE DEPLETION BY 1-METHYL-4-PHENYL-TETRAHYDROPYRIDINE (MPTP) IN RODENTS [J].

FULLER, RW ;

STERANKA, LR .

LIFE SCIENCES, 1985, 36 (03) :243-247

[8] CONVERSION OF 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP) AND ITS 5-METHYL ANALOG INTO PYRIDINIUM SALTS [J].

GESSNER, W ;

BROSSI, A ;

SHEN, RS ;

FRITZ, RR ;

ABELL, CW .

HELVETICA CHIMICA ACTA, 1984, 67 (08) :2037-2042

[9]

GESSNER W, 1985, FEBS LETT

[10]

HEIKKILA RE, 1984, NATURE, V311, P467, DOI 10.1038/311467a0

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