THIN-LAYER CHROMATOGRAPHY MASS-SPECTROMETRY USING INFRARED-LASER DESORPTION

被引：19

作者：

FANIBANDA, T ^{[1
]}

MILNES, J ^{[1
]}

GORMALLY, J ^{[1
]}

机构：

[1] UNIV SALFORD,DEPT CHEM & APPL CHEM,SALFORD M5 4WT,LANCS,ENGLAND

来源：

INTERNATIONAL JOURNAL OF MASS SPECTROMETRY AND ION PROCESSES | 1994年 / 140卷

关键词：

LASER DESORPTION; LASER IONIZATION; NAPROXEN; THIN LAYER CHROMATOGRAPHY MASS SPECTROMETRY; TIME-OF-FLIGHT;

D O I：

10.1016/0168-1176(94)04084-2

中图分类号：

O64 [物理化学（理论化学）、化学物理学]; O56 [分子物理学、原子物理学];

学科分类号：

070203 ; 070304 ; 081704 ; 1406 ;

摘要：

The infrared laser desorption of the drug naproxen from silica thin layer chromatography (TLC) plates is described. Desorbed neutral molecules were ionized by two-photon ionization at a wavelength of 266 nm and mass spectra were recorded using a time-of-flight mass spectrometer. Particular features investigated were the sensitivity attainable and the effect of repeated irradiation of the same area of the TLC plate.

引用

页码：127 / 132

页数：6

共 9 条

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