THE ROLE OF OXYGEN IN THE PHOTOINDUCED ANTIVIRAL ACTIVITY OF HYPERICIN

被引：52

作者：

FEHR, MJ

CARPENTER, SL

PETRICH, JW

机构：

[1] IOWA STATE UNIV SCI & TECHNOL,DEPT MICROBIOL IMMUNOL & PREVENT MED,AMES,IA 50011

[2] IOWA STATE UNIV SCI & TECHNOL,DEPT CHEM,AMES,IA 50011

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1994年 / 4卷 / 11期

关键词：

D O I：

10.1016/S0960-894X(01)80357-7

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Hypericin displays photoinduced antiviral activity. We examine the photoinduced antiviral activity of hypericin under both oxygenated and hypoxic conditions and observe that hypericin is equally toxic under both conditions. These results indicate that while singlet oxygen may play a role in the antiviral activity of hypericin, it does not play a major role.

引用

页码：1339 / 1344

页数：6

共 23 条

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